CYP2F1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CYP2F1 at tissue level.

III. Associated gene sets

GO_1901170Biological processnaphthalene catabolic process
GO_0019373Biological processepoxygenase P450 pathway
GO_0006805Biological processxenobiotic metabolic process
GO_0009636Biological processresponse to toxic substance
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0005737Cellular componentcytoplasm
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0019825Molecular functionoxygen binding
GO_0004497Molecular functionmonooxygenase activity
GO_0005506Molecular functioniron ion binding
GO_0008392Molecular functionarachidonic acid epoxygenase activity
GO_0020037Molecular functionheme binding
GO_0070330Molecular functionaromatase activity
GO_0016712Molecular functionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

IV. Literature review

[source]
Gene nameCYP2F1
Protein nameCytochrome P450 2F1 (EC 1.14.14.1) (CYPIIF1)
Cytochrome P450 family 2 subfamily F member 1
Truncated cytochrome P450 2F1 variant
Synonyms
DescriptionFUNCTION: May be involved in the metabolism of various pneumotoxicants including naphthalene. Is able to dealkylate ethoxycoumarin, propoxycoumarin, and pentoxyresorufin but possesses no activity toward ethoxyresorufin and only trace dearylation activity toward benzyloxyresorufin. Bioactivates 3-methylindole (3MI) by dehydrogenation to the putative electrophile 3-methylene-indolenine. .

AccessionsH0YGI9
P24903
A7KAU4
ENST00000439903.2
ENST00000532164.2 [P24903-2]
ENST00000534009.1
ENST00000331105.7 [P24903-1]
A0A075B795