CYB5R2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CYB5R2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CYB5R2 at tissue level.

III. Associated gene sets

GO_0016126Biological processsterol biosynthetic process
GO_0015701Biological processbicarbonate transport
GO_0016020Cellular componentmembrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005739Cellular componentmitochondrion
GO_0005634Cellular componentnucleus
GO_0071949Molecular functionFAD binding
GO_0004128Molecular functioncytochrome-b5 reductase activity, acting on NAD(P)H
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCYB5R2
Protein nameNADH-cytochrome b5 reductase 2 (b5R.2) (EC 1.6.2.2)
cytochrome-b5 reductase (EC 1.6.2.2)
Synonyms
DescriptionFUNCTION: NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction (By similarity). Responsible for NADH-dependent lucigenin chemiluminescence in spermatozoa by reducing both lucigenin and 2-[4-iodophenyl]-3-[4-nitrophenyl]-5-[2,4-disulfophenyl]-2H tetrazolium monosodium salt (WST-1). .

AccessionsQ6BCY4
ENST00000533558.5 [Q6BCY4-1]
ENST00000531096.5
ENST00000524790.5 [Q6BCY4-2]
E9PMI2
E9PQW2
E9PIV9
E9PRM4
ENST00000436351.2
ENST00000299498.11 [Q6BCY4-1]
ENST00000524608.5
ENST00000527542.5