CYB561 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0022900Biological processelectron transport chain
GO_0006879Biological processintracellular iron ion homeostasis
GO_0140576Biological processascorbate homeostasis
GO_0042584Cellular componentchromaffin granule membrane
GO_0005765Cellular componentlysosomal membrane
GO_0016020Cellular componentmembrane
GO_0140575Molecular functiontransmembrane monodehydroascorbate reductase activity
GO_0016491Molecular functionoxidoreductase activity
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameCYB561
Protein nameCytochrome b561
Transmembrane ascorbate-dependent reductase CYB561 (Cytochrome b-561) (Cytochrome b561)
Transmembrane ascorbate-dependent reductase CYB561 (EC 7.2.1.-) (Cytochrome b-561) (Cytochrome b561)
SynonymshCG_41832
DescriptionFUNCTION: Transmembrane reductase that uses ascorbate as an electron donor in the cytoplasm and transfers electrons across membranes to reduce monodehydro-L-ascorbate radical in the lumen of secretory vesicles. It is therefore involved the regeneration and homeostasis within secretory vesicles of ascorbate which in turn provides reducing equivalents needed to support the activity of intravesicular enzymes. .

AccessionsF5H757
ENST00000578072.1
ENST00000580691.5
ENST00000582997.5
J3KSL5
ENST00000582034.5
ENST00000542042.5
ENST00000360793.8 [P49447-1]
ENST00000581573.5 [P49447-1]
J3QR25
J3QLS0
J3QRF9
ENST00000584291.5 [P49447-1]
J3QS09
ENST00000392976.5 [P49447-1]
J3QS47
ENST00000584031.5
ENST00000448884.6 [P49447-2]
ENST00000582297.5
J3QKN3
ENST00000580592.1
ENST00000392975.6 [P49447-1]
J3QRH5
ENST00000585153.1
P49447