Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 30% ± 8% |
Insufficient scRNA-seq data for expression of CXXC1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 3951.67 | 1445 / 1445 | 100% | 26.25 | 183 / 183 |
| ovary | 100% | 4711.14 | 180 / 180 | 100% | 32.98 | 430 / 430 |
| pancreas | 100% | 4549.87 | 328 / 328 | 100% | 32.66 | 178 / 178 |
| thymus | 100% | 5505.79 | 653 / 653 | 100% | 44.44 | 605 / 605 |
| uterus | 100% | 5003.72 | 170 / 170 | 100% | 53.70 | 459 / 459 |
| skin | 100% | 4566.82 | 1809 / 1809 | 100% | 44.36 | 471 / 472 |
| adrenal gland | 100% | 5128.36 | 258 / 258 | 100% | 28.48 | 229 / 230 |
| brain | 100% | 3412.73 | 2629 / 2642 | 100% | 47.41 | 705 / 705 |
| intestine | 100% | 4533.59 | 966 / 966 | 99% | 31.12 | 524 / 527 |
| prostate | 100% | 5488.02 | 245 / 245 | 99% | 41.11 | 499 / 502 |
| liver | 100% | 2609.50 | 226 / 226 | 99% | 24.05 | 403 / 406 |
| kidney | 100% | 4226.07 | 89 / 89 | 99% | 34.59 | 894 / 901 |
| breast | 100% | 4038.23 | 459 / 459 | 99% | 33.93 | 1109 / 1118 |
| lung | 100% | 3686.55 | 577 / 578 | 99% | 33.37 | 1145 / 1155 |
| stomach | 100% | 3822.57 | 359 / 359 | 99% | 27.40 | 283 / 286 |
| bladder | 100% | 4833.81 | 21 / 21 | 99% | 49.91 | 498 / 504 |
| adipose | 100% | 3387.34 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 34.60 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 86.47 | 29 / 29 |
| spleen | 100% | 6103.64 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 52.94 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 28.57 | 1 / 1 |
| blood vessel | 100% | 3583.71 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 2064.93 | 855 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 98% | 3549.66 | 914 / 929 | 0% | 0 | 0 / 0 |
| muscle | 98% | 1765.04 | 787 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
| GO_0006355 | Biological process | regulation of DNA-templated transcription |
| GO_0016363 | Cellular component | nuclear matrix |
| GO_0016607 | Cellular component | nuclear speck |
| GO_0048188 | Cellular component | Set1C/COMPASS complex |
| GO_0035097 | Cellular component | histone methyltransferase complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005634 | Cellular component | nucleus |
| GO_0035064 | Molecular function | methylated histone binding |
| GO_0000987 | Molecular function | cis-regulatory region sequence-specific DNA binding |
| GO_0045322 | Molecular function | unmethylated CpG binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0008270 | Molecular function | zinc ion binding |
| Gene name | CXXC1 |
| Protein name | CXXC-type zinc finger protein 1 (CpG-binding protein) (PHD finger and CXXC domain-containing protein 1) CXXC finger protein 1 CXXC-type zinc finger protein 1 |
| Synonyms | hCG_23689 CFP1 PCCX1 CGBP PHF18 |
| Description | FUNCTION: Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG. . |
| Accessions | A0A669KB29 ENST00000586837.1 ENST00000591474.5 K7EQZ1 ENST00000673786.1 ENST00000412036.6 [Q9P0U4-2] ENST00000589940.5 K7EKZ6 A0A669KB50 ENST00000285106.11 [Q9P0U4-1] Q9P0U4 K7EQ21 K7EJR0 ENST00000589548.6 ENST00000587396.1 |