CTBP1-DT report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CTBP1-DT at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CTBP1-DT at tissue level.

III. Associated gene sets

GO_0000725Biological processrecombinational repair
GO_0006301Biological processpostreplication repair
GO_0005694Cellular componentchromosome
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCTBP1-DT
Protein nameDNA damage up-regulated protein (DDUP)
Synonyms
DescriptionFUNCTION: Promotes DNA damage repair through both homologous recombination repair (HRR) and post-replication repair (PRR) mechanisms . Enhances the retention of DNA damage response protein RAD18 at sites of DNA damage . This allows for HRR via association of RAD18 with RAD51C and for PRR via RAD18-mediated promotion of PCNA monoubiquitination . .

AccessionsC0HM98