Insufficient scRNA-seq data for expression of CST5 at single-cell level.
Insufficient scRNA-seq data for expression of CST5 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 90% | 33.17 | 523 / 578 | 24% | 0.99 | 282 / 1155 |
| adrenal gland | 74% | 28.81 | 191 / 258 | 19% | 34.86 | 44 / 230 |
| pancreas | 53% | 6.39 | 175 / 328 | 33% | 1.07 | 58 / 178 |
| esophagus | 54% | 63.50 | 786 / 1445 | 15% | 0.41 | 27 / 183 |
| ovary | 1% | 0.08 | 2 / 180 | 58% | 9.33 | 250 / 430 |
| thymus | 2% | 0.17 | 15 / 653 | 51% | 4.46 | 308 / 605 |
| kidney | 31% | 3.94 | 28 / 89 | 20% | 1.74 | 178 / 901 |
| prostate | 33% | 5.42 | 80 / 245 | 9% | 0.51 | 44 / 502 |
| breast | 1% | 0.36 | 5 / 459 | 34% | 62.30 | 375 / 1118 |
| bladder | 10% | 1.29 | 2 / 21 | 11% | 1.89 | 55 / 504 |
| skin | 0% | 0.06 | 8 / 1809 | 16% | 17.18 | 76 / 472 |
| intestine | 5% | 0.82 | 53 / 966 | 9% | 0.72 | 49 / 527 |
| liver | 2% | 0.13 | 4 / 226 | 12% | 0.68 | 48 / 406 |
| stomach | 2% | 0.12 | 6 / 359 | 11% | 0.53 | 31 / 286 |
| uterus | 0% | 0 | 0 / 170 | 6% | 0.78 | 26 / 459 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 1.80 | 1 / 45 |
| adipose | 1% | 0.06 | 9 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0.03 | 4 / 1335 | 0% | 0 | 0 / 0 |
| brain | 0% | 0.02 | 4 / 2642 | 0% | 0 | 0 / 705 |
| peripheral blood | 0% | 0.01 | 1 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_2000117 | Biological process | negative regulation of cysteine-type endopeptidase activity |
| GO_0005615 | Cellular component | extracellular space |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005576 | Cellular component | extracellular region |
| GO_0031982 | Cellular component | vesicle |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0004869 | Molecular function | cysteine-type endopeptidase inhibitor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | CST5 |
| Protein name | Cystatin-D (Cystatin-5) |
| Synonyms | |
| Description | FUNCTION: Cysteine proteinase inhibitor that possibly plays a protective role against proteinases present in the oral cavity. The order of preference for inhibition is cathepsin S > cathepsin H > cathepsin L > cathepsin B. . |
| Accessions | ENST00000304710.5 P28325 |