Insufficient scRNA-seq data for expression of CST5 at single-cell level.
Insufficient scRNA-seq data for expression of CST5 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 90% | 33.17 | 523 / 578 | 24% | 0.99 | 282 / 1155 |
adrenal gland | 74% | 28.81 | 191 / 258 | 19% | 34.86 | 44 / 230 |
pancreas | 53% | 6.39 | 175 / 328 | 33% | 1.07 | 58 / 178 |
esophagus | 54% | 63.50 | 786 / 1445 | 15% | 0.41 | 27 / 183 |
ovary | 1% | 0.08 | 2 / 180 | 58% | 9.33 | 250 / 430 |
thymus | 2% | 0.17 | 15 / 653 | 51% | 4.46 | 308 / 605 |
kidney | 31% | 3.94 | 28 / 89 | 20% | 1.74 | 178 / 901 |
prostate | 33% | 5.42 | 80 / 245 | 9% | 0.51 | 44 / 502 |
breast | 1% | 0.36 | 5 / 459 | 34% | 62.30 | 375 / 1118 |
bladder | 10% | 1.29 | 2 / 21 | 11% | 1.89 | 55 / 504 |
skin | 0% | 0.06 | 8 / 1809 | 16% | 17.18 | 76 / 472 |
intestine | 5% | 0.82 | 53 / 966 | 9% | 0.72 | 49 / 527 |
liver | 2% | 0.13 | 4 / 226 | 12% | 0.68 | 48 / 406 |
stomach | 2% | 0.12 | 6 / 359 | 11% | 0.53 | 31 / 286 |
uterus | 0% | 0 | 0 / 170 | 6% | 0.78 | 26 / 459 |
tonsil | 0% | 0 | 0 / 0 | 2% | 1.80 | 1 / 45 |
adipose | 1% | 0.06 | 9 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 0% | 0.03 | 4 / 1335 | 0% | 0 | 0 / 0 |
brain | 0% | 0.02 | 4 / 2642 | 0% | 0 | 0 / 705 |
peripheral blood | 0% | 0.01 | 1 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_2000117 | Biological process | negative regulation of cysteine-type endopeptidase activity |
GO_0005615 | Cellular component | extracellular space |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005576 | Cellular component | extracellular region |
GO_0031982 | Cellular component | vesicle |
GO_0005737 | Cellular component | cytoplasm |
GO_0004869 | Molecular function | cysteine-type endopeptidase inhibitor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | CST5 |
Protein name | Cystatin-D (Cystatin-5) |
Synonyms | |
Description | FUNCTION: Cysteine proteinase inhibitor that possibly plays a protective role against proteinases present in the oral cavity. The order of preference for inhibition is cathepsin S > cathepsin H > cathepsin L > cathepsin B. . |
Accessions | ENST00000304710.5 P28325 |