CST4 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CST4 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CST4 at tissue level.

III. Associated gene sets

GO_0001580Biological processdetection of chemical stimulus involved in sensory perception of bitter taste
GO_0045861Biological processnegative regulation of proteolysis
GO_2000117Biological processnegative regulation of cysteine-type endopeptidase activity
GO_0005615Cellular componentextracellular space
GO_0070062Cellular componentextracellular exosome
GO_0031982Cellular componentvesicle
GO_0005737Cellular componentcytoplasm
GO_0004869Molecular functioncysteine-type endopeptidase inhibitor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCST4
Protein nameCystatin-S (Cystatin-4) (Cystatin-SA-III) (Salivary acidic protein 1)
Synonyms
DescriptionFUNCTION: This protein strongly inhibits papain and ficin, partially inhibits stem bromelain and bovine cathepsin C, but does not inhibit porcine cathepsin B or clostripain. Papain is inhibited non-competitively.

AccessionsP01036
ENST00000217423.4