CSNK2A3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CSNK2A3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CSNK2A3 at tissue level.

III. Associated gene sets

GO_0008284Biological processpositive regulation of cell population proliferation
GO_0045732Biological processpositive regulation of protein catabolic process
GO_0018107Biological processpeptidyl-threonine phosphorylation
GO_0018105Biological processpeptidyl-serine phosphorylation
GO_0006468Biological processprotein phosphorylation
GO_0030307Biological processpositive regulation of cell growth
GO_0051726Biological processregulation of cell cycle
GO_0005956Cellular componentprotein kinase CK2 complex
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005634Cellular componentnucleus
GO_0004674Molecular functionprotein serine/threonine kinase activity
GO_0106310Molecular functionprotein serine kinase activity
GO_0005515Molecular functionprotein binding
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameCSNK2A3
Protein nameCasein kinase II subunit alpha 3 (CK II alpha 3) (EC 2.7.11.1) (Casein kinase II alpha 1 polypeptide pseudogene)
SynonymsCSNK2A1P
DescriptionFUNCTION: Probable catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Amplification-dependent oncogene; promotes cell proliferation and tumorigenesis by down-regulating expression of the tumor suppressor protein, PML. May play a role in the pathogenesis of the lung cancer development and progression. .

AccessionsQ8NEV1
ENST00000528848.3