Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| CD4-positive, alpha-beta T cell | 4 studies | 16% ± 1% | |
| CD8-positive, alpha-beta T cell | 4 studies | 16% ± 1% | |
| epithelial cell | 4 studies | 32% ± 13% | |
| endothelial cell | 3 studies | 23% ± 5% | |
| fibroblast | 3 studies | 20% ± 5% |
Insufficient scRNA-seq data for expression of CSKMT at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| ovary | 100% | 273.29 | 180 / 180 | 100% | 6.61 | 430 / 430 |
| prostate | 100% | 235.84 | 245 / 245 | 100% | 7.31 | 502 / 502 |
| esophagus | 100% | 184.04 | 1445 / 1445 | 98% | 3.12 | 180 / 183 |
| thymus | 100% | 172.10 | 653 / 653 | 98% | 3.80 | 595 / 605 |
| brain | 99% | 103.13 | 2614 / 2642 | 99% | 3.16 | 699 / 705 |
| stomach | 100% | 142.44 | 358 / 359 | 98% | 3.37 | 280 / 286 |
| bladder | 100% | 192.43 | 21 / 21 | 98% | 3.64 | 492 / 504 |
| pancreas | 100% | 140.50 | 327 / 328 | 98% | 2.40 | 174 / 178 |
| intestine | 100% | 178.59 | 966 / 966 | 97% | 3.55 | 513 / 527 |
| uterus | 100% | 226.75 | 170 / 170 | 97% | 3.55 | 446 / 459 |
| breast | 100% | 165.83 | 459 / 459 | 97% | 3.56 | 1086 / 1118 |
| lung | 100% | 148.99 | 577 / 578 | 97% | 2.86 | 1122 / 1155 |
| skin | 100% | 160.34 | 1801 / 1809 | 92% | 2.93 | 435 / 472 |
| kidney | 100% | 150.26 | 89 / 89 | 82% | 1.65 | 739 / 901 |
| adrenal gland | 100% | 277.34 | 258 / 258 | 67% | 1.59 | 155 / 230 |
| liver | 99% | 99.22 | 224 / 226 | 56% | 1.21 | 227 / 406 |
| eye | 0% | 0 | 0 / 0 | 100% | 5.20 | 80 / 80 |
| spleen | 100% | 200.83 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 4.92 | 1 / 1 |
| adipose | 100% | 161.66 | 1202 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 128.40 | 1328 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 98% | 148.87 | 789 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 2.58 | 44 / 45 |
| heart | 94% | 69.26 | 813 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 93% | 3.69 | 27 / 29 |
| peripheral blood | 88% | 78.91 | 822 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006479 | Biological process | protein methylation |
| GO_0018023 | Biological process | peptidyl-lysine trimethylation |
| GO_0018027 | Biological process | peptidyl-lysine dimethylation |
| GO_0018026 | Biological process | peptidyl-lysine monomethylation |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0016278 | Molecular function | lysine N-methyltransferase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0016279 | Molecular function | protein-lysine N-methyltransferase activity |
| Gene name | CSKMT |
| Protein name | Citrate synthase-lysine N-methyltransferase CSKMT, mitochondrial (CS-KMT) (EC 2.1.1.-) (Methyltransferase-like protein 12, mitochondrial) |
| Synonyms | METTL12 |
| Description | FUNCTION: Protein-lysine methyltransferase that selectively trimethylates citrate synthase (CS) in mitochondria . Seems to conduct trimethylation in a highly distributive manner rather than in a processive manner, and thus introduces a single methyl group per binding event . . |
| Accessions | ENST00000532971.2 A8MUP2 |