Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 9 studies | 34% ± 20% | |
| astrocyte | 8 studies | 25% ± 9% | |
| interneuron | 5 studies | 30% ± 21% | |
| GABAergic neuron | 5 studies | 34% ± 17% | |
| neuron | 4 studies | 25% ± 7% | |
| granule cell | 4 studies | 28% ± 7% | |
| microglial cell | 4 studies | 21% ± 3% | |
| macrophage | 4 studies | 21% ± 3% | |
| oligodendrocyte | 4 studies | 19% ± 3% | |
| endothelial cell | 3 studies | 35% ± 9% | |
| epithelial cell | 3 studies | 27% ± 11% | |
| oligodendrocyte precursor cell | 3 studies | 23% ± 4% | |
| fibroblast | 3 studies | 18% ± 1% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 9 studies | 29% ± 14% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 3553.80 | 653 / 653 | 100% | 29.66 | 604 / 605 |
| ovary | 100% | 1992.96 | 180 / 180 | 100% | 24.53 | 428 / 430 |
| brain | 100% | 10175.14 | 2629 / 2642 | 100% | 38.78 | 702 / 705 |
| prostate | 100% | 2569.56 | 244 / 245 | 99% | 15.76 | 498 / 502 |
| intestine | 100% | 2048.33 | 966 / 966 | 96% | 8.96 | 505 / 527 |
| adrenal gland | 99% | 1933.34 | 255 / 258 | 97% | 26.85 | 223 / 230 |
| breast | 99% | 1908.21 | 456 / 459 | 96% | 11.44 | 1074 / 1118 |
| skin | 95% | 1434.07 | 1727 / 1809 | 98% | 14.94 | 463 / 472 |
| kidney | 100% | 2413.83 | 89 / 89 | 93% | 9.41 | 842 / 901 |
| stomach | 99% | 1839.24 | 354 / 359 | 94% | 9.69 | 268 / 286 |
| bladder | 100% | 2131.38 | 21 / 21 | 89% | 8.47 | 450 / 504 |
| uterus | 99% | 2294.68 | 169 / 170 | 88% | 10.23 | 403 / 459 |
| lung | 96% | 1648.77 | 555 / 578 | 91% | 9.16 | 1047 / 1155 |
| pancreas | 90% | 1119.24 | 295 / 328 | 96% | 10.71 | 171 / 178 |
| esophagus | 87% | 1617.22 | 1255 / 1445 | 96% | 10.04 | 176 / 183 |
| liver | 76% | 753.64 | 172 / 226 | 62% | 4.47 | 252 / 406 |
| eye | 0% | 0 | 0 / 0 | 100% | 22.81 | 80 / 80 |
| spleen | 100% | 2102.73 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 6.57 | 1 / 1 |
| adipose | 100% | 1802.65 | 1199 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 1837.62 | 1323 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 98% | 1594.42 | 788 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 7.41 | 28 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 93% | 7.41 | 42 / 45 |
| heart | 84% | 1023.02 | 719 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 45% | 478.00 | 416 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0097009 | Biological process | energy homeostasis |
| GO_0007613 | Biological process | memory |
| GO_0032793 | Biological process | positive regulation of CREB transcription factor activity |
| GO_0043153 | Biological process | entrainment of circadian clock by photoperiod |
| GO_1902631 | Biological process | negative regulation of membrane hyperpolarization |
| GO_0051289 | Biological process | protein homotetramerization |
| GO_0048511 | Biological process | rhythmic process |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0016604 | Cellular component | nuclear body |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0005515 | Molecular function | protein binding |
| GO_0008140 | Molecular function | cAMP response element binding protein binding |
| Gene name | CRTC1 |
| Protein name | CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1) (Transducer of regulated cAMP response element-binding protein 1) (TORC-1) (Transducer of CREB protein 1) CREB regulated transcription coactivator 1 |
| Synonyms | MECT1 WAMTP1 TORC1 KIAA0616 |
| Description | FUNCTION: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons (By similarity). In concert with SIK1, regulates the light-induced entrainment of the circadian clock. In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock. .; FUNCTION: (Microbial infection) Plays a role of coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR). . |
| Accessions | ENST00000338797.10 [Q6UUV9-2] M0QXN6 ENST00000321949.13 [Q6UUV9-1] ENST00000601916.1 M0QX46 ENST00000594658.5 Q6UUV9 |