CRNN report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CRNN at tissue level.

III. Associated gene sets

GO_0051092Biological processpositive regulation of NF-kappaB transcription factor activity
GO_0051896Biological processregulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO_0010468Biological processregulation of gene expression
GO_0009408Biological processresponse to heat
GO_0071345Biological processcellular response to cytokine stimulus
GO_1902808Biological processpositive regulation of cell cycle G1/S phase transition
GO_0098609Biological processcell-cell adhesion
GO_0010838Biological processpositive regulation of keratinocyte proliferation
GO_0070062Cellular componentextracellular exosome
GO_0016020Cellular componentmembrane
GO_0005737Cellular componentcytoplasm
GO_0048306Molecular functioncalcium-dependent protein binding
GO_0005509Molecular functioncalcium ion binding
GO_0046914Molecular functiontransition metal ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCRNN
Protein nameCornulin (53 kDa putative calcium-binding protein) (53 kDa squamous epithelial-induced stress protein) (58 kDa heat shock protein) (Squamous epithelial heat shock protein 53) (Tumor-related protein)
SynonymsC1orf10
PDRC1
DRC1
SEP53
DescriptionFUNCTION: Promotes cell proliferation, G1/S cell cycle progression and induces expression of the cell cycle regulator CCND1 . Regulates proliferation induced by pro-inflammatory cytokine response via activation of NFKB1 and PI3K/AKT signaling pathways . .

AccessionsQ9UBG3
ENST00000271835.3