CPT2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CPT2 at tissue level.

III. Associated gene sets

GO_0006635Biological processfatty acid beta-oxidation
GO_0006853Biological processcarnitine shuttle
GO_0009437Biological processcarnitine metabolic process
GO_0001676Biological processlong-chain fatty acid metabolic process
GO_0001701Biological processin utero embryonic development
GO_0120162Biological processpositive regulation of cold-induced thermogenesis
GO_0005730Cellular componentnucleolus
GO_0005654Cellular componentnucleoplasm
GO_0005743Cellular componentmitochondrial inner membrane
GO_0005739Cellular componentmitochondrion
GO_0008458Molecular functioncarnitine O-octanoyltransferase activity
GO_0016746Molecular functionacyltransferase activity
GO_0005515Molecular functionprotein binding
GO_0004095Molecular functioncarnitine O-palmitoyltransferase activity

IV. Literature review

[source]
Gene nameCPT2
Protein nameCarnitine palmitoyltransferase 2
Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II)
Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II)
SynonymsCPT1
DescriptionFUNCTION: Involved in the intramitochondrial synthesis of acylcarnitines from accumulated acyl-CoA metabolites . Reconverts acylcarnitines back into the respective acyl-CoA esters that can then undergo beta-oxidation, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Active with medium (C8-C12) and long-chain (C14-C18) acyl-CoA esters . .

AccessionsENST00000636935.1
A0A1B0GVF3
A0A1B0GTM0
ENST00000636239.1
ENST00000371486.4
ENST00000635888.1
A0A1B0GTB8
A0A1B0GTL9
P23786
A0A1B0GWC0
ENST00000636891.1
ENST00000635862.1
A0A1B0GUB8
A0A1B0GV75
A0A1B0GUD9
ENST00000638135.1
ENST00000637252.1
ENST00000636867.1