CPN1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CPN1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CPN1 at tissue level.

III. Associated gene sets

GO_0006518Biological processpeptide metabolic process
GO_0016485Biological processprotein processing
GO_0051384Biological processresponse to glucocorticoid
GO_0010815Biological processbradykinin catabolic process
GO_0030163Biological processprotein catabolic process
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0005515Molecular functionprotein binding
GO_0008270Molecular functionzinc ion binding
GO_0004181Molecular functionmetallocarboxypeptidase activity

IV. Literature review

[source]
Gene nameCPN1
Protein nameCarboxypeptidase N subunit 1
Carboxypeptidase N catalytic chain (CPN) (EC 3.4.17.3) (Anaphylatoxin inactivator) (Arginine carboxypeptidase) (Carboxypeptidase N polypeptide 1) (Carboxypeptidase N small subunit) (Kininase-1) (Lysine carboxypeptidase) (Plasma carboxypeptidase B) (Serum carboxypeptidase N) (SCPN)
SynonymsACBP
DescriptionFUNCTION: Protects the body from potent vasoactive and inflammatory peptides containing C-terminal Arg or Lys (such as kinins or anaphylatoxins) which are released into the circulation.

AccessionsENST00000441382.1
B1AP58
ENST00000370418.8
P15169