Insufficient scRNA-seq data for expression of CORT at single-cell level.
Insufficient scRNA-seq data for expression of CORT at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 99% | 695.83 | 2626 / 2642 | 60% | 1.31 | 425 / 705 |
| prostate | 97% | 78.43 | 237 / 245 | 25% | 0.37 | 125 / 502 |
| uterus | 81% | 43.95 | 137 / 170 | 41% | 0.73 | 187 / 459 |
| kidney | 100% | 115.93 | 89 / 89 | 20% | 0.31 | 178 / 901 |
| thymus | 99% | 85.95 | 649 / 653 | 17% | 0.26 | 104 / 605 |
| intestine | 93% | 55.11 | 895 / 966 | 11% | 0.16 | 57 / 527 |
| adrenal gland | 85% | 44.04 | 220 / 258 | 17% | 0.27 | 39 / 230 |
| ovary | 83% | 43.61 | 150 / 180 | 19% | 0.33 | 80 / 430 |
| ureter | 0% | 0 | 0 / 0 | 100% | 1.54 | 1 / 1 |
| esophagus | 69% | 32.10 | 1000 / 1445 | 18% | 0.30 | 33 / 183 |
| bladder | 62% | 31.38 | 13 / 21 | 24% | 0.45 | 122 / 504 |
| liver | 77% | 41.29 | 174 / 226 | 7% | 0.10 | 27 / 406 |
| lung | 65% | 31.50 | 377 / 578 | 15% | 0.25 | 178 / 1155 |
| breast | 67% | 31.12 | 309 / 459 | 12% | 0.17 | 136 / 1118 |
| stomach | 72% | 32.89 | 259 / 359 | 5% | 0.05 | 13 / 286 |
| spleen | 75% | 34.18 | 180 / 241 | 0% | 0 | 0 / 0 |
| adipose | 64% | 29.98 | 767 / 1204 | 0% | 0 | 0 / 0 |
| skin | 52% | 20.95 | 940 / 1809 | 8% | 0.13 | 38 / 472 |
| pancreas | 38% | 15.40 | 123 / 328 | 17% | 0.26 | 31 / 178 |
| tonsil | 0% | 0 | 0 / 0 | 31% | 0.49 | 14 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 31% | 0.40 | 9 / 29 |
| peripheral blood | 23% | 9.85 | 215 / 929 | 0% | 0 | 0 / 0 |
| blood vessel | 22% | 8.51 | 291 / 1335 | 0% | 0 | 0 / 0 |
| heart | 19% | 6.93 | 167 / 861 | 0% | 0 | 0 / 0 |
| muscle | 5% | 2.18 | 41 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.01 | 1 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007193 | Biological process | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway |
| GO_0030334 | Biological process | regulation of cell migration |
| GO_0007268 | Biological process | chemical synaptic transmission |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0045202 | Cellular component | synapse |
| GO_0005184 | Molecular function | neuropeptide hormone activity |
| GO_0001664 | Molecular function | G protein-coupled receptor binding |
| Gene name | CORT |
| Protein name | Cortistatin [Cleaved into: Cortistatin-29; Cortistatin-17] CORT protein |
| Synonyms | UNQ307/PRO350 |
| Description | FUNCTION: Binds to all human somatostatin receptor (SSTR) subtypes. It also inhibits cAMP production induced by forskolin through SSTRs. |
| Accessions | ENST00000377049.4 Q8IUV6 O00230 |