CORT report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CORT at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CORT at tissue level.

III. Associated gene sets

GO_0007193Biological processadenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO_0030334Biological processregulation of cell migration
GO_0007268Biological processchemical synaptic transmission
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0045202Cellular componentsynapse
GO_0005184Molecular functionneuropeptide hormone activity
GO_0001664Molecular functionG protein-coupled receptor binding

IV. Literature review

[source]
Gene nameCORT
Protein nameCortistatin [Cleaved into: Cortistatin-29; Cortistatin-17]
CORT protein
SynonymsUNQ307/PRO350
DescriptionFUNCTION: Binds to all human somatostatin receptor (SSTR) subtypes. It also inhibits cAMP production induced by forskolin through SSTRs.

AccessionsENST00000377049.4
Q8IUV6
O00230