COMMD5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCOMMD5
Protein nameCOMM domain-containing protein 5 (Hypertension-related calcium-regulated gene protein) (HCaRG)
COMM domain-containing protein 5
COMM domain containing 5
SynonymsHT002
DescriptionFUNCTION: May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes . Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis (By similarity). Down-regulates activation of NF-kappa-B . .

AccessionsQ9GZQ3
ENST00000402718.4
E9PJE4
ENST00000543949.2
ENST00000305103.4
ENST00000533270.1
ENST00000529143.1
H0YEQ6
ENST00000530332.1
ENST00000450361.2