Insufficient scRNA-seq data for expression of COL8A2 at single-cell level.
Insufficient scRNA-seq data for expression of COL8A2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
thymus | 97% | 1748.49 | 634 / 653 | 90% | 87.16 | 542 / 605 |
breast | 84% | 1341.65 | 387 / 459 | 92% | 56.69 | 1032 / 1118 |
uterus | 96% | 1247.34 | 163 / 170 | 79% | 32.57 | 362 / 459 |
lung | 90% | 823.35 | 523 / 578 | 71% | 18.92 | 823 / 1155 |
prostate | 95% | 1435.81 | 233 / 245 | 64% | 9.69 | 322 / 502 |
ovary | 83% | 656.51 | 149 / 180 | 70% | 17.93 | 300 / 430 |
esophagus | 97% | 2086.94 | 1406 / 1445 | 52% | 13.10 | 96 / 183 |
bladder | 100% | 2968.76 | 21 / 21 | 47% | 10.55 | 237 / 504 |
skin | 78% | 848.51 | 1402 / 1809 | 45% | 8.49 | 211 / 472 |
intestine | 77% | 866.09 | 742 / 966 | 37% | 7.16 | 193 / 527 |
stomach | 65% | 1726.31 | 234 / 359 | 48% | 9.27 | 136 / 286 |
blood vessel | 100% | 6154.33 | 1334 / 1335 | 0% | 0 | 0 / 0 |
spleen | 98% | 1877.86 | 237 / 241 | 0% | 0 | 0 / 0 |
pancreas | 4% | 18.98 | 12 / 328 | 85% | 32.63 | 152 / 178 |
tonsil | 0% | 0 | 0 / 0 | 87% | 25.05 | 39 / 45 |
adipose | 79% | 935.56 | 950 / 1204 | 0% | 0 | 0 / 0 |
brain | 28% | 293.37 | 727 / 2642 | 45% | 9.03 | 316 / 705 |
lymph node | 0% | 0 | 0 / 0 | 62% | 12.09 | 18 / 29 |
kidney | 18% | 146.33 | 16 / 89 | 31% | 5.42 | 275 / 901 |
heart | 46% | 438.05 | 395 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 25% | 3.13 | 20 / 80 |
adrenal gland | 10% | 65.68 | 27 / 258 | 1% | 0.07 | 2 / 230 |
liver | 1% | 3.97 | 2 / 226 | 7% | 1.62 | 29 / 406 |
peripheral blood | 4% | 21.54 | 39 / 929 | 0% | 0 | 0 / 0 |
muscle | 3% | 23.14 | 26 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0001525 | Biological process | angiogenesis |
GO_0030198 | Biological process | extracellular matrix organization |
GO_0001935 | Biological process | endothelial cell proliferation |
GO_0098609 | Biological process | cell-cell adhesion |
GO_0048593 | Biological process | camera-type eye morphogenesis |
GO_0005604 | Cellular component | basement membrane |
GO_0005615 | Cellular component | extracellular space |
GO_0005788 | Cellular component | endoplasmic reticulum lumen |
GO_0005581 | Cellular component | collagen trimer |
GO_0005576 | Cellular component | extracellular region |
GO_0062023 | Cellular component | collagen-containing extracellular matrix |
GO_0031012 | Cellular component | extracellular matrix |
GO_0005201 | Molecular function | extracellular matrix structural constituent |
GO_0030020 | Molecular function | extracellular matrix structural constituent conferring tensile strength |
GO_0030674 | Molecular function | protein-macromolecule adaptor activity |
Gene name | COL8A2 |
Protein name | Collagen alpha-2(VIII) chain (Endothelial collagen) Collagen type VIII alpha 2 COL8A2 protein |
Synonyms | |
Description | FUNCTION: Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also a component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis (By similarity). . |
Accessions | R9UH47 P25067 E9PP49 ENST00000481785.1 Q4VAQ1 R9UH34 R9UJ55 Q4VAP9 Q4VAQ0 ENST00000397799.2 ENST00000303143.9 |