COASY report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of COASY at tissue level.

III. Associated gene sets

GO_0015937Biological processcoenzyme A biosynthetic process
GO_0005741Cellular componentmitochondrial outer membrane
GO_0070062Cellular componentextracellular exosome
GO_0005759Cellular componentmitochondrial matrix
GO_0004595Molecular functionpantetheine-phosphate adenylyltransferase activity
GO_0004140Molecular functiondephospho-CoA kinase activity
GO_0005515Molecular functionprotein binding
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameCOASY
Protein nameCoenzyme A synthase
Bifunctional coenzyme A synthase (CoA synthase) (NBP) (POV-2) [Includes: Phosphopantetheine adenylyltransferase (EC 2.7.7.3) (Dephospho-CoA pyrophosphorylase) (Pantetheine-phosphate adenylyltransferase) (PPAT); Dephospho-CoA kinase (DPCK) (EC 2.7.1.24) (Dephosphocoenzyme A kinase) (DPCOAK)]
SynonymsPSEC0106
DescriptionFUNCTION: Bifunctional enzyme that catalyzes the fourth and fifth sequential steps of CoA biosynthetic pathway. The fourth reaction is catalyzed by the phosphopantetheine adenylyltransferase, coded by the coaD domain; the fifth reaction is catalyzed by the dephospho-CoA kinase, coded by the coaE domain. May act as a point of CoA biosynthesis regulation. .

AccessionsQ13057
ENST00000587157.1
ENST00000421097.6 [Q13057-1]
K7EPT0
K7EP09
ENST00000585811.1
ENST00000586771.1
ENST00000585909.1
K7EQ60
ENST00000591779.5
K7ES73
K7EPC2
ENST00000590958.5 [Q13057-2]
ENST00000587858.5
K7EN91
ENST00000393818.3 [Q13057-1]
K7ESK6
ENST00000587214.1