CNTD1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CNTD1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CNTD1 at tissue level.

III. Associated gene sets

GO_0007131Biological processreciprocal meiotic recombination
GO_0007283Biological processspermatogenesis
GO_0051445Biological processregulation of meiotic cell cycle
GO_0005694Cellular componentchromosome
GO_0035861Cellular componentsite of double-strand break
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus

IV. Literature review

[source]
Gene nameCNTD1
Protein nameCyclin N-terminal domain containing 1
Cyclin N-terminal domain-containing protein 1
Cyclin N-terminal domain containing 1 (Cyclin N-terminal domain containing, isoform CRA_b) (cDNA FLJ50910)
SynonymshCG_16966
CNTD
DescriptionFUNCTION: Plays a role in the different steps of crossover formation during meiotic recombination. Participates in the crossover differentiation step of crossover-specific recombination intermediates through its interaction with PRR19. In addition, stimulates crossover formation through the interactions with RFC3 and RFC4 and simultaneously regulates cell-cycle progression through interactions with CDC34 and subsequent ubiquitination of WEE1. May also participates in an active deselection process that destabilizes or removes excess pre-CO intermediates. .

AccessionsK7ERX8
ENST00000585355.5
ENST00000588527.5
K7ELB6
K7EQE2
ENST00000592166.5
Q8N815
B4DXR6
ENST00000586652.1
ENST00000588408.6 [Q8N815-1]