Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 6 studies | 31% ± 16% | |
| ciliated cell | 4 studies | 31% ± 12% | |
| GABAergic neuron | 3 studies | 25% ± 2% | |
| glutamatergic neuron | 3 studies | 32% ± 5% | |
| basal cell | 3 studies | 23% ± 6% | |
| goblet cell | 3 studies | 19% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| bladder | 100% | 2451.33 | 21 / 21 | 100% | 92.78 | 504 / 504 |
| breast | 100% | 2043.91 | 459 / 459 | 100% | 81.52 | 1118 / 1118 |
| esophagus | 100% | 2797.19 | 1445 / 1445 | 100% | 86.28 | 183 / 183 |
| intestine | 100% | 2848.60 | 966 / 966 | 100% | 100.83 | 527 / 527 |
| liver | 100% | 1920.12 | 226 / 226 | 100% | 52.65 | 406 / 406 |
| ovary | 100% | 1587.32 | 180 / 180 | 100% | 65.09 | 430 / 430 |
| pancreas | 100% | 1983.31 | 328 / 328 | 100% | 73.27 | 178 / 178 |
| prostate | 100% | 2338.79 | 245 / 245 | 100% | 64.21 | 502 / 502 |
| skin | 100% | 2535.58 | 1809 / 1809 | 100% | 68.94 | 472 / 472 |
| stomach | 100% | 2619.81 | 359 / 359 | 100% | 91.70 | 286 / 286 |
| uterus | 100% | 2013.46 | 170 / 170 | 100% | 79.06 | 459 / 459 |
| lung | 100% | 2042.40 | 576 / 578 | 100% | 91.66 | 1155 / 1155 |
| thymus | 100% | 1920.15 | 653 / 653 | 100% | 47.47 | 602 / 605 |
| kidney | 100% | 2420.18 | 89 / 89 | 99% | 61.59 | 896 / 901 |
| brain | 99% | 1200.24 | 2615 / 2642 | 100% | 39.94 | 705 / 705 |
| adrenal gland | 100% | 2308.29 | 258 / 258 | 97% | 40.91 | 223 / 230 |
| adipose | 100% | 1851.04 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 48.54 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 77.51 | 29 / 29 |
| muscle | 100% | 2349.81 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 3330.38 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 63.56 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 79.60 | 1 / 1 |
| heart | 100% | 2151.88 | 859 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1671.44 | 1331 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 94% | 2184.90 | 876 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0031047 | Biological process | regulatory ncRNA-mediated gene silencing |
| GO_0006417 | Biological process | regulation of translation |
| GO_0000289 | Biological process | nuclear-transcribed mRNA poly(A) tail shortening |
| GO_0030014 | Cellular component | CCR4-NOT complex |
| GO_0005829 | Cellular component | cytosol |
| GO_0005634 | Cellular component | nucleus |
| GO_0005515 | Molecular function | protein binding |
| GO_0003674 | Molecular function | molecular_function |
| Gene name | CNOT11 |
| Protein name | CCR4-NOT transcription complex subunit 11 |
| Synonyms | C2orf29 C40 |
| Description | FUNCTION: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is required for the association of CNOT10 with the CCR4-NOT complex. Seems not to be required for complex deadenylase function. |
| Accessions | Q9UKZ1 ENST00000289382.8 ENST00000420107.1 H7C0C7 |
