CNEP1R1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CNEP1R1 at tissue level.

III. Associated gene sets

GO_0035307Biological processpositive regulation of protein dephosphorylation
GO_0006629Biological processlipid metabolic process
GO_0034504Biological processprotein localization to nucleus
GO_0010867Biological processpositive regulation of triglyceride biosynthetic process
GO_0071595Cellular componentNem1-Spo7 phosphatase complex
GO_0005829Cellular componentcytosol
GO_0031965Cellular componentnuclear membrane
GO_0005635Cellular componentnuclear envelope
GO_0005737Cellular componentcytoplasm
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCNEP1R1
Protein nameNuclear envelope phosphatase-regulatory subunit 1 (NEP1-R1) (Transmembrane protein 188)
Nuclear envelope phosphatase-regulatory subunit 1 (Transmembrane protein 188)
SynonymsTMEM188
C16orf69
DescriptionFUNCTION: Forms with the serine/threonine protein phosphatase CTDNEP1 an active complex which dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol. .

AccessionsENST00000566482.5 [Q8N9A8-3]
Q8N9A8
ENST00000389134.9
ENST00000427478.7 [Q8N9A8-1]
ENST00000568890.5 [Q8N9A8-3]
H3BLY8
ENST00000565457.5 [Q8N9A8-1]
ENST00000458059.7 [Q8N9A8-2]
ENST00000566093.1
H3BMF1
H3BN40
ENST00000562576.5
ENST00000565556.5
H3BUT5