Name | Number of supported studies | Average coverage | |
---|---|---|---|
glutamatergic neuron | 3 studies | 25% ± 7% |
Insufficient scRNA-seq data for expression of CNEP1R1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 865.77 | 1445 / 1445 | 100% | 9.06 | 183 / 183 |
lung | 100% | 1049.73 | 578 / 578 | 100% | 11.49 | 1155 / 1155 |
brain | 100% | 941.01 | 2640 / 2642 | 100% | 15.41 | 705 / 705 |
breast | 100% | 811.61 | 459 / 459 | 100% | 10.69 | 1117 / 1118 |
kidney | 100% | 619.55 | 89 / 89 | 100% | 11.53 | 900 / 901 |
adrenal gland | 100% | 897.59 | 258 / 258 | 100% | 13.55 | 229 / 230 |
ovary | 100% | 788.50 | 180 / 180 | 100% | 8.04 | 428 / 430 |
bladder | 100% | 709.95 | 21 / 21 | 99% | 9.96 | 501 / 504 |
stomach | 100% | 628.82 | 358 / 359 | 100% | 8.61 | 285 / 286 |
thymus | 100% | 615.02 | 653 / 653 | 99% | 8.02 | 601 / 605 |
intestine | 100% | 862.86 | 966 / 966 | 99% | 9.16 | 523 / 527 |
uterus | 100% | 917.68 | 170 / 170 | 99% | 10.40 | 455 / 459 |
prostate | 100% | 755.36 | 245 / 245 | 99% | 7.01 | 497 / 502 |
pancreas | 100% | 426.28 | 327 / 328 | 98% | 9.25 | 175 / 178 |
skin | 100% | 1068.92 | 1809 / 1809 | 98% | 10.77 | 461 / 472 |
liver | 100% | 516.96 | 226 / 226 | 94% | 5.19 | 381 / 406 |
adipose | 100% | 964.13 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 10.87 | 29 / 29 |
spleen | 100% | 1507.75 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 8.48 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 6.45 | 1 / 1 |
muscle | 100% | 655.90 | 801 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 99% | 689.57 | 1327 / 1335 | 0% | 0 | 0 / 0 |
heart | 99% | 626.98 | 854 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 96% | 1265.31 | 895 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 83% | 4.38 | 66 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0035307 | Biological process | positive regulation of protein dephosphorylation |
GO_0006629 | Biological process | lipid metabolic process |
GO_0034504 | Biological process | protein localization to nucleus |
GO_0010867 | Biological process | positive regulation of triglyceride biosynthetic process |
GO_0071595 | Cellular component | Nem1-Spo7 phosphatase complex |
GO_0005829 | Cellular component | cytosol |
GO_0031965 | Cellular component | nuclear membrane |
GO_0005635 | Cellular component | nuclear envelope |
GO_0005737 | Cellular component | cytoplasm |
GO_0005515 | Molecular function | protein binding |
Gene name | CNEP1R1 |
Protein name | Nuclear envelope phosphatase-regulatory subunit 1 (NEP1-R1) (Transmembrane protein 188) Nuclear envelope phosphatase-regulatory subunit 1 (Transmembrane protein 188) |
Synonyms | TMEM188 C16orf69 |
Description | FUNCTION: Forms with the serine/threonine protein phosphatase CTDNEP1 an active complex which dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol. . |
Accessions | ENST00000566482.5 [Q8N9A8-3] Q8N9A8 ENST00000389134.9 ENST00000427478.7 [Q8N9A8-1] ENST00000568890.5 [Q8N9A8-3] H3BLY8 ENST00000565457.5 [Q8N9A8-1] ENST00000458059.7 [Q8N9A8-2] ENST00000566093.1 H3BMF1 H3BN40 ENST00000562576.5 ENST00000565556.5 H3BUT5 |