CMTR2 | OmnibusX

Name	Number of supported studies	Average coverage
epithelial cell	4 studies	26% ± 5%	Explore
microglial cell	4 studies	17% ± 2%	Explore

Name	Number of supported studies	Average coverage
brain	3 studies	18% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	1471.45	1445 / 1445	100%	15.58	183 / 183
breast	100%	1473.30	459 / 459	100%	15.37	1115 / 1118
intestine	100%	1367.98	966 / 966	99%	13.02	524 / 527
bladder	100%	1115.57	21 / 21	99%	11.78	500 / 504
thymus	100%	1826.49	653 / 653	99%	13.81	599 / 605
kidney	100%	1398.93	89 / 89	99%	11.36	892 / 901
lung	99%	1211.75	572 / 578	100%	12.77	1155 / 1155
pancreas	100%	896.35	328 / 328	99%	11.26	176 / 178
prostate	100%	1506.01	245 / 245	99%	11.29	496 / 502
ovary	100%	1087.58	180 / 180	98%	7.67	423 / 430
stomach	99%	915.17	355 / 359	99%	12.52	284 / 286
uterus	100%	1169.75	170 / 170	98%	10.44	450 / 459
brain	96%	517.97	2528 / 2642	100%	10.18	704 / 705
skin	100%	1387.91	1807 / 1809	94%	9.61	446 / 472
adrenal gland	100%	1726.73	258 / 258	94%	7.15	217 / 230
liver	100%	1256.24	226 / 226	87%	5.25	354 / 406
lymph node	0%	0	0 / 0	100%	9.82	29 / 29
spleen	100%	2073.82	241 / 241	0%	0	0 / 0
adipose	100%	1193.94	1203 / 1204	0%	0	0 / 0
blood vessel	98%	715.65	1307 / 1335	0%	0	0 / 0
muscle	97%	594.05	778 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	96%	8.78	43 / 45
heart	94%	645.58	811 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	80%	5.89	64 / 80
peripheral blood	65%	869.13	603 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

Gene name	CMTR2
Protein name	Cap methyltransferase 2 Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.296) (Cap methyltransferase 2) (Cap2 2'O-ribose methyltransferase 2) (HMTr2) (MTr2) (FtsJ methyltransferase domain-containing protein 1) (Protein adrift homolog)
Synonyms	FTSJD1 AFT
Description	FUNCTION: S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap2 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the second nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) (cap0) to produce m(7)GpppRmpNm (cap2). Recognizes a guanosine cap on RNA independently of its N(7) methylation status. Display cap2 methylation on both cap0 and cap1. Displays a preference for cap1 RNAs. .
Accessions	H3BNZ8 H3BR19 ENST00000564183.1 ENST00000565850.1 ENST00000338099.9 H3BUK2 H3BTZ7 Q8IYT2 ENST00000563876.1 ENST00000567610.1 ENST00000434935.7 ENST00000568910.1 H3BS00

GO_0006370	Biological process	7-methylguanosine mRNA capping
GO_0032259	Biological process	methylation
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0004483	Molecular function	mRNA (nucleoside-2'-O-)-methyltransferase activity

CMTR2 report