CLTRN report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CLTRN at tissue level.

III. Associated gene sets

GO_0051957Biological processpositive regulation of amino acid transport
GO_0017156Biological processcalcium-ion regulated exocytosis
GO_1905737Biological processpositive regulation of L-proline import across plasma membrane
GO_0022898Biological processregulation of transmembrane transporter activity
GO_0035493Biological processSNARE complex assembly
GO_0035773Biological processinsulin secretion involved in cellular response to glucose stimulus
GO_0031526Cellular componentbrush border membrane
GO_0070062Cellular componentextracellular exosome
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0042803Molecular functionprotein homodimerization activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCLTRN
Protein nameCollectrin (Transmembrane protein 27)
Collectrin, amino acid transport regulator
SynonymsTMEM27
UNQ679/PRO1312
DescriptionFUNCTION: Plays an important role in amino acid transport by acting as binding partner of amino acid transporters SLC6A18 and SLC6A19, regulating their trafficking on the cell surface and their amino acid transporter activity (By similarity). May also play a role in trafficking of amino acid transporters SLC3A1 and SLC7A9 to the renal cortical cell membrane (By similarity). Regulator of SNARE complex function . Stimulator of beta cell replication . .

AccessionsENST00000380342.4
ENST00000650271.1
A0A3B3ITM8
Q9HBJ8