CLIC5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007601Biological processvisual perception
GO_0007605Biological processsensory perception of sound
GO_1902476Biological processchloride transmembrane transport
GO_0006821Biological processchloride transport
GO_0007565Biological processfemale pregnancy
GO_0005813Cellular componentcentrosome
GO_0016324Cellular componentapical plasma membrane
GO_0015629Cellular componentactin cytoskeleton
GO_0070062Cellular componentextracellular exosome
GO_0034707Cellular componentchloride channel complex
GO_0005938Cellular componentcell cortex
GO_0005794Cellular componentGolgi apparatus
GO_0120044Cellular componentstereocilium base
GO_0005739Cellular componentmitochondrion
GO_0005515Molecular functionprotein binding
GO_0005254Molecular functionchloride channel activity

IV. Literature review

[source]
Gene nameCLIC5
Protein nameCLIC5 protein
Chloride intracellular channel protein 5
Chloride intracellular channel 5
Chloride intracellular channel protein
SynonymshCG_2001062
DescriptionFUNCTION: Required for normal hearing . It is necessary for the formation of stereocilia in the inner ear and normal development of the organ of Corti (By similarity). Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. May play a role in the regulation of transepithelial ion absorption and secretion. Is required for the development and/or maintenance of the proper glomerular endothelial cell and podocyte architecture . Plays a role in formation of the lens suture in the eye, which is important for normal optical properties of the lens (By similarity). .

AccessionsA0A5F9ZHK1
ENST00000642250.1
Q53G01
A0A2R8Y4M1
A0A2R8Y615
Q9NZA1
ENST00000644878.1
A0A2R8YGW2
Q49AE1
Q8N675
ENST00000644324.1
ENST00000672327.1
ENST00000544153.3 [Q9NZA1-3]
ENST00000339561.12 [Q9NZA1-2]
ENST00000185206.12 [Q9NZA1-1]