Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 50% ± 12% | |
| progenitor cell | 3 studies | 57% ± 8% |
Insufficient scRNA-seq data for expression of CLDN6 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 86% | 38.21 | 282 / 328 | 26% | 4.89 | 46 / 178 |
| ovary | 13% | 0.68 | 23 / 180 | 93% | 223.83 | 398 / 430 |
| ureter | 0% | 0 | 0 / 0 | 100% | 57.47 | 1 / 1 |
| brain | 85% | 26.40 | 2256 / 2642 | 0% | 0.00 | 1 / 705 |
| lung | 51% | 4.44 | 293 / 578 | 24% | 23.26 | 278 / 1155 |
| thymus | 44% | 4.15 | 286 / 653 | 13% | 0.67 | 81 / 605 |
| kidney | 54% | 8.49 | 48 / 89 | 2% | 0.35 | 19 / 901 |
| uterus | 25% | 1.59 | 43 / 170 | 17% | 23.47 | 76 / 459 |
| skin | 34% | 2.24 | 611 / 1809 | 1% | 0.33 | 6 / 472 |
| stomach | 19% | 1.76 | 70 / 359 | 14% | 8.51 | 41 / 286 |
| prostate | 29% | 1.82 | 72 / 245 | 0% | 0.01 | 1 / 502 |
| peripheral blood | 27% | 1.95 | 251 / 929 | 0% | 0 | 0 / 0 |
| esophagus | 11% | 0.58 | 165 / 1445 | 15% | 12.56 | 28 / 183 |
| muscle | 26% | 2.17 | 206 / 803 | 0% | 0 | 0 / 0 |
| breast | 15% | 0.97 | 71 / 459 | 8% | 4.64 | 93 / 1118 |
| blood vessel | 24% | 1.39 | 316 / 1335 | 0% | 0 | 0 / 0 |
| heart | 23% | 1.44 | 202 / 861 | 0% | 0 | 0 / 0 |
| liver | 17% | 1.57 | 38 / 226 | 6% | 1.97 | 24 / 406 |
| intestine | 12% | 0.81 | 117 / 966 | 9% | 11.98 | 48 / 527 |
| adipose | 13% | 0.68 | 152 / 1204 | 0% | 0 | 0 / 0 |
| bladder | 5% | 0.29 | 1 / 21 | 8% | 8.01 | 39 / 504 |
| spleen | 12% | 0.94 | 28 / 241 | 0% | 0 | 0 / 0 |
| adrenal gland | 10% | 0.61 | 27 / 258 | 0% | 0 | 0 / 230 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.08 | 1 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0046718 | Biological process | symbiont entry into host cell |
| GO_0016338 | Biological process | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules |
| GO_0007155 | Biological process | cell adhesion |
| GO_0070830 | Biological process | bicellular tight junction assembly |
| GO_0016327 | Cellular component | apicolateral plasma membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005923 | Cellular component | bicellular tight junction |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0001618 | Molecular function | virus receptor activity |
| GO_0005198 | Molecular function | structural molecule activity |
| Gene name | CLDN6 |
| Protein name | Claudin-6 (Skullin) Claudin 6 |
| Synonyms | UNQ757/PRO1488 |
| Description | FUNCTION: Plays a major role in tight junction-specific obliteration of the intercellular space. .; FUNCTION: (Microbial infection) Acts as a receptor for hepatitis C virus (HCV) entry into hepatic cells. . |
| Accessions | ENST00000572154.1 ENST00000396925.1 I3L1E7 P56747 ENST00000328796.5 |