Name | Number of supported studies | Average coverage | |
---|---|---|---|
glutamatergic neuron | 9 studies | 41% ± 25% | |
oligodendrocyte precursor cell | 8 studies | 25% ± 8% | |
GABAergic neuron | 8 studies | 38% ± 21% | |
endothelial cell | 7 studies | 30% ± 12% | |
interneuron | 7 studies | 36% ± 22% | |
astrocyte | 7 studies | 31% ± 12% | |
oligodendrocyte | 7 studies | 25% ± 8% | |
macrophage | 6 studies | 24% ± 6% | |
epithelial cell | 6 studies | 27% ± 6% | |
neuron | 5 studies | 31% ± 10% | |
microglial cell | 5 studies | 25% ± 6% | |
retinal cone cell | 5 studies | 22% ± 6% | |
granule cell | 4 studies | 19% ± 4% | |
ciliated cell | 4 studies | 20% ± 4% | |
GABAergic interneuron | 3 studies | 22% ± 8% | |
lymphocyte | 3 studies | 16% ± 1% | |
hematopoietic precursor cell | 3 studies | 21% ± 2% | |
megakaryocyte-erythroid progenitor cell | 3 studies | 28% ± 8% | |
transit amplifying cell | 3 studies | 42% ± 18% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 4653.91 | 1445 / 1445 | 100% | 80.36 | 183 / 183 |
stomach | 100% | 4104.51 | 359 / 359 | 100% | 57.33 | 286 / 286 |
brain | 100% | 7782.86 | 2641 / 2642 | 100% | 82.01 | 705 / 705 |
breast | 100% | 4445.71 | 459 / 459 | 100% | 76.78 | 1116 / 1118 |
intestine | 100% | 5016.76 | 966 / 966 | 100% | 55.13 | 525 / 527 |
bladder | 100% | 4899.86 | 21 / 21 | 100% | 48.85 | 502 / 504 |
skin | 100% | 8005.54 | 1808 / 1809 | 99% | 63.18 | 468 / 472 |
ovary | 100% | 7676.32 | 180 / 180 | 99% | 44.44 | 426 / 430 |
prostate | 100% | 4239.90 | 245 / 245 | 99% | 41.55 | 496 / 502 |
uterus | 100% | 5296.74 | 170 / 170 | 98% | 54.79 | 452 / 459 |
lung | 99% | 3868.31 | 573 / 578 | 99% | 52.31 | 1144 / 1155 |
adrenal gland | 100% | 10140.26 | 258 / 258 | 98% | 40.83 | 225 / 230 |
thymus | 100% | 3429.60 | 652 / 653 | 97% | 29.18 | 585 / 605 |
kidney | 99% | 2719.09 | 88 / 89 | 93% | 25.71 | 842 / 901 |
pancreas | 94% | 1892.84 | 308 / 328 | 98% | 34.46 | 174 / 178 |
liver | 100% | 3294.66 | 226 / 226 | 90% | 23.33 | 364 / 406 |
adipose | 100% | 4337.74 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 5215.84 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 50.35 | 29 / 29 |
muscle | 100% | 7720.81 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 3930.45 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 61.16 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 10.95 | 1 / 1 |
eye | 0% | 0 | 0 / 0 | 96% | 31.77 | 77 / 80 |
heart | 94% | 4118.75 | 812 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 49% | 3588.71 | 455 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007019 | Biological process | microtubule depolymerization |
GO_0050658 | Biological process | RNA transport |
GO_0030951 | Biological process | establishment or maintenance of microtubule cytoskeleton polarity |
GO_0007052 | Biological process | mitotic spindle organization |
GO_0051298 | Biological process | centrosome duplication |
GO_0051301 | Biological process | cell division |
GO_0007098 | Biological process | centrosome cycle |
GO_0046785 | Biological process | microtubule polymerization |
GO_0090063 | Biological process | positive regulation of microtubule nucleation |
GO_0007051 | Biological process | spindle organization |
GO_0005730 | Cellular component | nucleolus |
GO_0005886 | Cellular component | plasma membrane |
GO_0000922 | Cellular component | spindle pole |
GO_0016020 | Cellular component | membrane |
GO_0005813 | Cellular component | centrosome |
GO_0000776 | Cellular component | kinetochore |
GO_0035371 | Cellular component | microtubule plus-end |
GO_0032991 | Cellular component | protein-containing complex |
GO_0005829 | Cellular component | cytosol |
GO_0015630 | Cellular component | microtubule cytoskeleton |
GO_0005737 | Cellular component | cytoplasm |
GO_0061863 | Molecular function | microtubule plus end polymerase |
GO_0051010 | Molecular function | microtubule plus-end binding |
GO_0045296 | Molecular function | cadherin binding |
GO_0043021 | Molecular function | ribonucleoprotein complex binding |
GO_0008017 | Molecular function | microtubule binding |
GO_0005515 | Molecular function | protein binding |
Gene name | CKAP5 |
Protein name | Cytoskeleton associated protein 5 CKAP5 protein Cytoskeleton-associated protein 5 (Colonic and hepatic tumor overexpressed gene protein) (Ch-TOG) |
Synonyms | KIAA0097 |
Description | FUNCTION: Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Acts as a processive microtubule polymerase. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles. In spindle formation protects kinetochore microtubules from depolymerization by KIF2C and has an essential role in centrosomal microtubule assembly independently of KIF2C activity. Contributes to centrosome integrity. Acts as a component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension . Enhances the strength of NDC80 complex-mediated kinetochore-tip microtubule attachments . . |
Accessions | ENST00000312055.9 [Q14008-2] ENST00000529230.6 [Q14008-1] H0YEK7 E9PQH5 H0YDX5 ENST00000525896.1 ENST00000527333.5 ENST00000526876.2 Q8IYN5 H0YCF6 Q14008 ENST00000354558.7 [Q14008-2] ENST00000526496.1 |