Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 10 studies | 53% ± 26% | |
| oligodendrocyte precursor cell | 10 studies | 30% ± 12% | |
| GABAergic neuron | 8 studies | 47% ± 26% | |
| interneuron | 6 studies | 36% ± 19% | |
| neuron | 4 studies | 27% ± 10% | |
| GABAergic interneuron | 3 studies | 35% ± 10% | |
| granule cell | 3 studies | 24% ± 8% | |
| transit amplifying cell | 3 studies | 45% ± 23% | |
| astrocyte | 3 studies | 30% ± 14% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 10 studies | 38% ± 25% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 7662.23 | 2639 / 2642 | 94% | 8.75 | 664 / 705 |
| esophagus | 84% | 993.30 | 1217 / 1445 | 92% | 6.44 | 168 / 183 |
| stomach | 90% | 1196.47 | 323 / 359 | 84% | 3.63 | 241 / 286 |
| intestine | 91% | 1273.97 | 875 / 966 | 82% | 3.80 | 434 / 527 |
| kidney | 98% | 2195.00 | 87 / 89 | 74% | 7.67 | 665 / 901 |
| adrenal gland | 100% | 2719.62 | 258 / 258 | 65% | 4.22 | 149 / 230 |
| skin | 77% | 1509.98 | 1389 / 1809 | 88% | 6.00 | 413 / 472 |
| lung | 72% | 1370.86 | 417 / 578 | 86% | 9.55 | 989 / 1155 |
| spleen | 100% | 2792.29 | 241 / 241 | 0% | 0 | 0 / 0 |
| uterus | 8% | 79.44 | 13 / 170 | 91% | 5.28 | 419 / 459 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 8.21 | 44 / 45 |
| bladder | 5% | 29.95 | 1 / 21 | 78% | 4.50 | 392 / 504 |
| breast | 10% | 76.39 | 48 / 459 | 64% | 2.65 | 714 / 1118 |
| ovary | 3% | 31.16 | 5 / 180 | 55% | 2.25 | 237 / 430 |
| lymph node | 0% | 0 | 0 / 0 | 52% | 1.97 | 15 / 29 |
| thymus | 22% | 191.39 | 144 / 653 | 18% | 1.16 | 106 / 605 |
| pancreas | 0% | 2.04 | 1 / 328 | 28% | 0.98 | 50 / 178 |
| peripheral blood | 22% | 910.65 | 206 / 929 | 0% | 0 | 0 / 0 |
| adipose | 18% | 150.62 | 217 / 1204 | 0% | 0 | 0 / 0 |
| liver | 2% | 14.56 | 4 / 226 | 11% | 0.34 | 45 / 406 |
| prostate | 10% | 100.80 | 25 / 245 | 3% | 0.09 | 13 / 502 |
| eye | 0% | 0 | 0 / 0 | 13% | 0.33 | 10 / 80 |
| blood vessel | 6% | 55.73 | 76 / 1335 | 0% | 0 | 0 / 0 |
| heart | 5% | 46.24 | 47 / 861 | 0% | 0 | 0 / 0 |
| muscle | 1% | 11.84 | 10 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0000278 | Biological process | mitotic cell cycle |
| GO_0000281 | Biological process | mitotic cytokinesis |
| GO_0048699 | Biological process | generation of neurons |
| GO_0051402 | Biological process | neuron apoptotic process |
| GO_0032467 | Biological process | positive regulation of cytokinesis |
| GO_0035331 | Biological process | negative regulation of hippo signaling |
| GO_0016020 | Cellular component | membrane |
| GO_0005829 | Cellular component | cytosol |
| GO_0106310 | Molecular function | protein serine kinase activity |
| GO_0030291 | Molecular function | protein serine/threonine kinase inhibitor activity |
| GO_0019901 | Molecular function | protein kinase binding |
| GO_0004674 | Molecular function | protein serine/threonine kinase activity |
| GO_0001223 | Molecular function | transcription coactivator binding |
| GO_0030165 | Molecular function | PDZ domain binding |
| GO_0097110 | Molecular function | scaffold protein binding |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0005524 | Molecular function | ATP binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0017124 | Molecular function | SH3 domain binding |
| Gene name | CIT |
| Protein name | non-specific serine/threonine protein kinase (EC 2.7.11.1) Citron rho-interacting serine/threonine kinase Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21) |
| Synonyms | CRIK STK21 KIAA0949 |
| Description | FUNCTION: Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Displays serine/threonine protein kinase activity. Plays an important role in the regulation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/MLC2. . |
| Accessions | H0YGG8 ENST00000676849.1 ENST00000536325.1 ENST00000392521.7 [O14578-4] ENST00000261833.11 [O14578-1] ENST00000677812.1 A0A7I2YQJ8 ENST00000678652.1 A0A7I2V692 A0A7I2V4A6 F5H4K4 ENST00000678686.1 A0A7I2V365 ENST00000677849.1 ENST00000546026.2 A0A7I2V4H7 ENST00000392520.2 ENST00000677438.1 ENST00000678494.1 H7BYJ3 ENST00000679120.1 ENST00000678087.1 A0A7I2V4I0 ENST00000677993.1 A0A7I2V2G7 ENST00000676563.1 ENST00000679249.1 O14578 ENST00000678677.1 A0A7I2V426 |
