CINP report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0042273Biological processribosomal large subunit biogenesis
GO_0006281Biological processDNA repair
GO_0051301Biological processcell division
GO_0006260Biological processDNA replication
GO_0005634Cellular componentnucleus
GO_1990275Molecular functionpreribosome binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCINP
Protein nameCyclin dependent kinase 2 interacting protein
Cyclin-dependent kinase 2-interacting protein (CDK2-interacting protein)
Synonyms
DescriptionFUNCTION: Component of the DNA replication complex, which interacts with two kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication . Regulates ATR-mediated checkpoint signaling in response to DNA damage . Also involved in the cytoplasmic maturation steps of pre-60S ribosomal particles by promoting the release of shuttling protein RSL24D1/RLP24 from the pre-ribosomal particles . Promotes maturation of pre-60S ribosome together with AFG2A, AFG2B and AIRIM . .

AccessionsENST00000216756.11 [Q9BW66-1]
ENST00000558764.1
ENST00000559504.5
ENST00000541568.6 [Q9BW66-2]
Q9BW66
H0YN33
H0YKY0
ENST00000559514.5 [Q9BW66-1]
ENST00000536961.6 [Q9BW66-3]