CIB2 | OmnibusX

Name	Number of supported studies	Average coverage
plasmacytoid dendritic cell	7 studies	27% ± 7%	Explore

Name	Number of supported studies	Average coverage
intestine	3 studies	19% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	468.46	2636 / 2642	99%	17.88	696 / 705
ovary	99%	312.14	179 / 180	96%	19.47	412 / 430
prostate	100%	587.06	244 / 245	92%	12.63	464 / 502
bladder	100%	459.57	21 / 21	92%	14.43	462 / 504
intestine	100%	516.18	965 / 966	89%	11.87	467 / 527
pancreas	92%	172.94	303 / 328	96%	8.67	170 / 178
uterus	100%	551.11	170 / 170	88%	16.77	403 / 459
kidney	100%	416.71	89 / 89	87%	9.62	781 / 901
adrenal gland	100%	642.23	258 / 258	86%	12.83	197 / 230
skin	90%	253.97	1625 / 1809	94%	17.56	443 / 472
thymus	96%	228.41	624 / 653	87%	16.31	525 / 605
esophagus	93%	358.67	1343 / 1445	86%	9.99	158 / 183
lung	85%	152.88	489 / 578	82%	11.77	949 / 1155
breast	99%	270.77	454 / 459	67%	6.53	753 / 1118
stomach	59%	171.62	213 / 359	84%	12.58	240 / 286
eye	0%	0	0 / 0	100%	19.24	80 / 80
ureter	0%	0	0 / 0	100%	6.76	1 / 1
adipose	99%	275.70	1190 / 1204	0%	0	0 / 0
muscle	97%	375.09	782 / 803	0%	0	0 / 0
heart	96%	1224.34	824 / 861	0%	0	0 / 0
blood vessel	96%	215.87	1275 / 1335	0%	0	0 / 0
spleen	95%	155.00	228 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	91%	8.37	41 / 45
lymph node	0%	0	0 / 0	79%	6.86	23 / 29
liver	8%	10.12	17 / 226	34%	3.46	139 / 406
peripheral blood	17%	21.95	154 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0055074	Biological process	calcium ion homeostasis
GO_0045494	Biological process	photoreceptor cell maintenance
GO_0071318	Biological process	cellular response to ATP
GO_0007204	Biological process	positive regulation of cytosolic calcium ion concentration
GO_0032420	Cellular component	stereocilium
GO_0031594	Cellular component	neuromuscular junction
GO_0001750	Cellular component	photoreceptor outer segment
GO_0042383	Cellular component	sarcolemma
GO_0001917	Cellular component	photoreceptor inner segment
GO_0072562	Cellular component	blood microparticle
GO_0032437	Cellular component	cuticular plate
GO_0005927	Cellular component	muscle tendon junction
GO_0071944	Cellular component	cell periphery
GO_0005737	Cellular component	cytoplasm
GO_0042803	Molecular function	protein homodimerization activity
GO_0000287	Molecular function	magnesium ion binding
GO_0005178	Molecular function	integrin binding
GO_0005509	Molecular function	calcium ion binding
GO_0005515	Molecular function	protein binding

Gene name	CIB2
Protein name	Calcium and integrin-binding family member 2 (Kinase-interacting protein 2) (KIP 2) Calcium and integrin binding family member 2
Synonyms	KIP2
Description	FUNCTION: Calcium- and integrin-binding protein that plays a role in intracellular calcium homeostasis (By similarity). Acts as an auxiliary subunit of the sensory mechanoelectrical transduction (MET) channel in hair cells (By similarity). Essential for mechanoelectrical transduction (MET) currents in auditory hair cells and thereby required for hearing (By similarity). Regulates the function of hair cell mechanotransduction by controlling the distribution of transmembrane channel-like proteins TMC1 and TMC2, and by regulating the function of the MET channels in hair cells (By similarity). Required for the maintenance of auditory hair cell stereocilia bundle morphology and function and for hair-cell survival in the cochlea (By similarity). Critical for proper photoreceptor cell maintenance and function (By similarity). Plays a role in intracellular calcium homeostasis by decreasing ATP-induced calcium release . .
Accessions	ENST00000559645.1 ENST00000643268.1 H0YKC8 H0YLL7 H0YND4 A0A2R8Y4Y2 ENST00000557846.5 [O75838-4] O75838 H0YLX3 ENST00000557917.5 ENST00000539011.5 [O75838-3] ENST00000560618.5 H0YML3 ENST00000557818.1 H0YKX8 ENST00000559054.1 ENST00000561190.5 ENST00000258930.8 [O75838-1]

CIB2 report