CHST13 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CHST13 at tissue level.

III. Associated gene sets

GO_0030166Biological processproteoglycan biosynthetic process
GO_0030206Biological processchondroitin sulfate biosynthetic process
GO_0016051Biological processcarbohydrate biosynthetic process
GO_0000139Cellular componentGolgi membrane
GO_0016020Cellular componentmembrane
GO_0001537Molecular functionN-acetylgalactosamine 4-O-sulfotransferase activity
GO_0008146Molecular functionsulfotransferase activity
GO_0005515Molecular functionprotein binding
GO_0047756Molecular functionchondroitin 4-sulfotransferase activity

IV. Literature review

[source]
Gene nameCHST13
Protein nameCHST13 protein
Carbohydrate sulfotransferase 13 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 3) (Chondroitin 4-sulfotransferase 3) (C4ST-3) (C4ST3)
Carbohydrate sulfotransferase (EC 2.8.2.-)
Synonyms
DescriptionFUNCTION: Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Transfers sulfate to the C4 hydroxyl of beta1,4-linked GalNAc that is substituted with a beta-linked glucuronic acid at the C-3 hydroxyl. No activity toward dermatan.

AccessionsQ3ZCU8
ENST00000319340.7 [Q8NET6-1]
Q3ZCR4
Q8NET6