CHRD report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CHRD at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CHRD at tissue level.

III. Associated gene sets

GO_0030509Biological processBMP signaling pathway
GO_0001501Biological processskeletal system development
GO_0030336Biological processnegative regulation of cell migration
GO_0002053Biological processpositive regulation of mesenchymal cell proliferation
GO_0045785Biological processpositive regulation of cell adhesion
GO_0030514Biological processnegative regulation of BMP signaling pathway
GO_0021513Biological processspinal cord dorsal/ventral patterning
GO_0045668Biological processnegative regulation of osteoblast differentiation
GO_0009953Biological processdorsal/ventral pattern formation
GO_0033504Biological processfloor plate development
GO_0005615Cellular componentextracellular space
GO_0019955Molecular functioncytokine binding
GO_0036122Molecular functionBMP binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCHRD
Protein nameChordin
SynonymsUNQ217/PRO243
DescriptionFUNCTION: Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes (By similarity). .

FUNCTION: Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. .

AccessionsENST00000348986.3 [Q9H2X0-5]
Q9H2X0
E7ESX1
ENST00000204604.6 [Q9H2X0-1]
ENST00000420973.5 [Q9H2X0-4]
ENST00000448472.5 [Q9H2X0-3]
ENST00000450923.5
ENST00000356534.7 [Q9H2X0-2]