CHP2 | OmnibusX

Name	Number of supported studies	Average coverage
intestine	3 studies	28% ± 12%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
intestine	52%	5310.61	504 / 966	65%	28.97	344 / 527
bladder	43%	802.76	9 / 21	54%	23.84	274 / 504
skin	71%	6443.18	1287 / 1809	6%	0.55	28 / 472
stomach	0%	0	0 / 359	60%	25.34	171 / 286
prostate	33%	320.52	82 / 245	25%	1.90	125 / 502
uterus	1%	7.11	2 / 170	38%	11.79	176 / 459
esophagus	0%	3.59	7 / 1445	37%	8.32	67 / 183
lung	2%	14.33	10 / 578	29%	6.74	334 / 1155
tonsil	0%	0	0 / 0	27%	4.87	12 / 45
pancreas	0%	0	0 / 328	21%	8.14	38 / 178
ovary	0%	0	0 / 180	17%	1.48	73 / 430
kidney	15%	84.75	13 / 89	1%	0.05	5 / 901
liver	0%	0	0 / 226	5%	1.69	22 / 406
adrenal gland	0%	0	0 / 258	3%	0.20	6 / 230
breast	0%	12.69	1 / 459	2%	0.49	21 / 1118
brain	1%	4.51	23 / 2642	0%	0.01	1 / 705
thymus	0%	0	0 / 653	1%	0.08	6 / 605
adipose	0%	3.97	3 / 1204	0%	0	0 / 0
muscle	0%	1.27	1 / 803	0%	0	0 / 0
blood vessel	0%	1.96	1 / 1335	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
heart	0%	0	0 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0070886	Biological process	positive regulation of calcineurin-NFAT signaling cascade
GO_0008284	Biological process	positive regulation of cell population proliferation
GO_0015031	Biological process	protein transport
GO_0010922	Biological process	positive regulation of phosphatase activity
GO_0042307	Biological process	positive regulation of protein import into nucleus
GO_0032417	Biological process	positive regulation of sodium:proton antiporter activity
GO_0071277	Biological process	cellular response to calcium ion
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0005730	Cellular component	nucleolus
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005886	Cellular component	plasma membrane
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0005509	Molecular function	calcium ion binding
GO_0005515	Molecular function	protein binding

Gene name	CHP2
Protein name	Calcineurin B homologous protein 2 (Hepatocellular carcinoma-associated antigen 520)
Synonyms	HCA520
Description	FUNCTION: Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing pH and protecting cells from serum deprivation-induced death. Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus. .
Accessions	ENST00000300113.3 O43745

CHP2 report