CHAT | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of CHAT at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
intestine	83%	19.88	798 / 966	1%	0.01	4 / 527
brain	34%	30.93	890 / 2642	7%	0.26	52 / 705
stomach	29%	5.46	103 / 359	1%	0.02	4 / 286
esophagus	16%	1.76	231 / 1445	2%	0.11	4 / 183
pancreas	13%	1.00	41 / 328	3%	0.04	5 / 178
adrenal gland	3%	0.21	7 / 258	7%	0.32	16 / 230
lung	1%	0.04	4 / 578	9%	0.57	100 / 1155
prostate	4%	0.54	11 / 245	5%	0.35	23 / 502
uterus	1%	0.04	1 / 170	6%	0.52	29 / 459
tonsil	0%	0	0 / 0	7%	0.25	3 / 45
thymus	0%	0	0 / 653	6%	0.25	38 / 605
ovary	0%	0	0 / 180	5%	0.11	22 / 430
kidney	0%	0	0 / 89	4%	0.43	37 / 901
lymph node	0%	0	0 / 0	3%	0.05	1 / 29
bladder	0%	0	0 / 21	3%	0.22	13 / 504
skin	2%	0.24	38 / 1809	0%	0.00	1 / 472
heart	2%	0.18	15 / 861	0%	0	0 / 0
liver	0%	0.05	1 / 226	0%	0.01	1 / 406
breast	0%	0.02	1 / 459	0%	0.01	5 / 1118
peripheral blood	1%	0.03	5 / 929	0%	0	0 / 0
blood vessel	0%	0.04	6 / 1335	0%	0	0 / 0
spleen	0%	0.02	1 / 241	0%	0	0 / 0
muscle	0%	0.02	3 / 803	0%	0	0 / 0
adipose	0%	0.03	4 / 1204	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0006656	Biological process	phosphatidylcholine biosynthetic process
GO_0008292	Biological process	acetylcholine biosynthetic process
GO_0007274	Biological process	neuromuscular synaptic transmission
GO_0006836	Biological process	neurotransmitter transport
GO_0005829	Cellular component	cytosol
GO_0045202	Cellular component	synapse
GO_0043005	Cellular component	neuron projection
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0004102	Molecular function	choline O-acetyltransferase activity

Gene name	CHAT
Protein name	Choline O-acetyltransferase Choline O-acetyltransferase (CHOACTase) (ChAT) (Choline acetylase) (EC 2.3.1.6) Choline O-acetyltransferase (EC 2.3.1.6)
Synonyms
Description	FUNCTION: Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses. . FUNCTION: Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses. .
Accessions	ENST00000351556.7 [P28329-3] A0A1W2PRG4 R4GN13 ENST00000640822.1 A0A1W2PP46 P28329 ENST00000395559.6 [P28329-3] ENST00000638282.1 ENST00000466590.6 ENST00000339797.5 [P28329-3] ENST00000337653.7 [P28329-1] ENST00000395562.2 [P28329-2]

CHAT report