I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| type I pneumocyte | 10 studies | 31% ± 10% | |
| ciliated cell | 10 studies | 28% ± 9% | |
| epithelial cell | 5 studies | 27% ± 9% | |
| enterocyte | 3 studies | 21% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| type I pneumocyte | 10 studies | 31% ± 10% | |
| ciliated cell | 10 studies | 28% ± 9% | |
| epithelial cell | 5 studies | 27% ± 9% | |
| enterocyte | 3 studies | 21% ± 4% |
Insufficient scRNA-seq data for expression of CGN at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 100% | 4702.66 | 328 / 328 | 94% | 76.08 | 168 / 178 |
| liver | 100% | 6266.39 | 226 / 226 | 90% | 54.02 | 366 / 406 |
| prostate | 87% | 2344.36 | 212 / 245 | 97% | 42.12 | 489 / 502 |
| lung | 98% | 5665.40 | 566 / 578 | 86% | 55.17 | 993 / 1155 |
| thymus | 98% | 1792.37 | 643 / 653 | 75% | 17.82 | 454 / 605 |
| stomach | 75% | 3528.14 | 270 / 359 | 97% | 57.82 | 278 / 286 |
| breast | 58% | 2069.57 | 265 / 459 | 95% | 54.00 | 1061 / 1118 |
| intestine | 50% | 5520.16 | 479 / 966 | 97% | 61.07 | 513 / 527 |
| ovary | 49% | 494.81 | 88 / 180 | 95% | 39.46 | 409 / 430 |
| kidney | 100% | 3462.43 | 89 / 89 | 39% | 8.07 | 355 / 901 |
| bladder | 52% | 1657.38 | 11 / 21 | 87% | 48.16 | 438 / 504 |
| esophagus | 39% | 1080.64 | 563 / 1445 | 69% | 46.97 | 126 / 183 |
| ureter | 0% | 0 | 0 / 0 | 100% | 12.02 | 1 / 1 |
| skin | 72% | 4185.01 | 1303 / 1809 | 15% | 2.09 | 70 / 472 |
| uterus | 7% | 159.19 | 12 / 170 | 70% | 28.21 | 320 / 459 |
| tonsil | 0% | 0 | 0 / 0 | 49% | 10.89 | 22 / 45 |
| brain | 42% | 842.92 | 1113 / 2642 | 2% | 0.45 | 17 / 705 |
| adipose | 30% | 1084.64 | 358 / 1204 | 0% | 0 | 0 / 0 |
| adrenal gland | 2% | 16.74 | 5 / 258 | 7% | 1.09 | 16 / 230 |
| heart | 4% | 58.18 | 36 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 2% | 16.28 | 19 / 929 | 0% | 0 | 0 / 0 |
| blood vessel | 1% | 10.81 | 12 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 1% | 9.74 | 2 / 241 | 0% | 0 | 0 / 0 |
| muscle | 0% | 1.32 | 1 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0008150 | Biological process | biological_process |
| GO_0000226 | Biological process | microtubule cytoskeleton organization |
| GO_0030054 | Cellular component | cell junction |
| GO_0016459 | Cellular component | myosin complex |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005923 | Cellular component | bicellular tight junction |
| GO_0008017 | Molecular function | microtubule binding |
| GO_0045296 | Molecular function | cadherin binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0003779 | Molecular function | actin binding |
| Gene name | CGN |
| Protein name | Cingulin |
| Synonyms | KIAA1319 |
| Description | FUNCTION: Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. FUNCTION: Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. . |
| Accessions | ENST00000427934.2 H0Y4A8 ENST00000271636.12 [Q9P2M7-1] B9EK46 Q9P2M7 A2A3M4 ENST00000505188.5 ENST00000502442.1 A6PVU7 ENST00000416743.1 |
