Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 7 studies | 26% ± 9% | |
GABAergic neuron | 7 studies | 38% ± 19% | |
fibroblast | 6 studies | 18% ± 4% | |
glutamatergic neuron | 5 studies | 49% ± 21% | |
astrocyte | 5 studies | 27% ± 5% | |
oligodendrocyte | 5 studies | 21% ± 3% | |
interneuron | 5 studies | 38% ± 20% | |
neuron | 4 studies | 29% ± 8% | |
epithelial cell | 4 studies | 25% ± 2% | |
oligodendrocyte precursor cell | 4 studies | 31% ± 8% | |
GABAergic interneuron | 3 studies | 20% ± 4% | |
microglial cell | 3 studies | 19% ± 3% | |
pericyte | 3 studies | 18% ± 3% | |
smooth muscle cell | 3 studies | 16% ± 0% | |
basal cell | 3 studies | 23% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
bladder | 100% | 3014.52 | 21 / 21 | 100% | 21.47 | 504 / 504 |
esophagus | 100% | 2336.33 | 1445 / 1445 | 100% | 16.64 | 183 / 183 |
intestine | 100% | 2310.98 | 966 / 966 | 100% | 14.50 | 527 / 527 |
ovary | 100% | 3390.69 | 180 / 180 | 100% | 20.55 | 430 / 430 |
prostate | 100% | 3054.57 | 245 / 245 | 100% | 19.95 | 502 / 502 |
skin | 100% | 3036.10 | 1809 / 1809 | 100% | 28.02 | 472 / 472 |
brain | 100% | 4856.54 | 2641 / 2642 | 100% | 29.42 | 705 / 705 |
breast | 100% | 2699.03 | 459 / 459 | 100% | 25.94 | 1117 / 1118 |
kidney | 100% | 2425.12 | 89 / 89 | 100% | 20.54 | 900 / 901 |
thymus | 100% | 2673.60 | 653 / 653 | 100% | 28.89 | 604 / 605 |
lung | 100% | 2449.02 | 577 / 578 | 100% | 20.81 | 1155 / 1155 |
uterus | 100% | 3591.87 | 170 / 170 | 100% | 25.46 | 458 / 459 |
stomach | 100% | 1621.26 | 359 / 359 | 100% | 13.55 | 285 / 286 |
adrenal gland | 100% | 1914.53 | 258 / 258 | 99% | 24.47 | 228 / 230 |
pancreas | 98% | 1102.62 | 323 / 328 | 100% | 22.93 | 178 / 178 |
liver | 82% | 589.09 | 185 / 226 | 90% | 9.23 | 365 / 406 |
adipose | 100% | 2584.05 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 3036.22 | 1335 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 23.34 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 26.08 | 29 / 29 |
spleen | 100% | 2955.99 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 19.46 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 19.39 | 1 / 1 |
heart | 97% | 1370.21 | 839 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 96% | 1835.64 | 895 / 929 | 0% | 0 | 0 / 0 |
muscle | 67% | 499.88 | 534 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0030148 | Biological process | sphingolipid biosynthetic process |
GO_0014003 | Biological process | oligodendrocyte development |
GO_0046513 | Biological process | ceramide biosynthetic process |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0003677 | Molecular function | DNA binding |
GO_0050291 | Molecular function | sphingosine N-acyltransferase activity |
Gene name | CERS5 |
Protein name | Ceramide synthase 5 (LASS5 protein) Ceramide synthase 5 Ceramide synthase 5 (CerS5) (LAG1 longevity assurance homolog 5) (Sphingoid base N-palmitoyltransferase CERS5) (EC 2.3.1.291) (Sphingosine N-acyltransferase CERS5) (EC 2.3.1.24) Ceramide synthase 5 (cDNA FLJ59959, moderately similar to LAG1 longevity assurance homolog 5) |
Synonyms | LASS5 |
Description | FUNCTION: Ceramide synthase that catalyzes the transfer of the acyl chain from acyl-CoA to a sphingoid base, with high selectivity toward palmitoyl-CoA (hexadecanoyl-CoA; C16:0-CoA). Can use other acyl donors, but with less efficiency (By similarity). N-acylates sphinganine and sphingosine bases to form dihydroceramides and ceramides in de novo synthesis and salvage pathways, respectively . Plays a role in de novo ceramide synthesis and surfactant homeostasis in pulmonary epithelia (By similarity). . |
Accessions | ENST00000550258.5 ENST00000547455.5 F8VY42 ENST00000438450.6 F8VXY1 ENST00000422340.6 [Q8N5B7-2] Q8N5B7 Q49AQ3 F8W1N7 ENST00000542320.5 F8W1Z3 H0YHK2 ENST00000553122.5 ENST00000317551.12 [Q8N5B7-1] H0YI10 ENST00000550919.5 ENST00000549389.5 F8W1K4 B4DQR7 ENST00000551697.5 ENST00000550547.5 H0YHG4 ENST00000550899.1 ENST00000547800.2 F8VSK7 ENST00000380189.8 F8VQZ6 ENST00000546514.1 ENST00000547787.5 H0YIG1 |