CEP72 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CEP72 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CEP72 at tissue level.

III. Associated gene sets

GO_0033566Biological processgamma-tubulin complex localization
GO_1904779Biological processregulation of protein localization to centrosome
GO_0007099Biological processcentriole replication
GO_0007051Biological processspindle organization
GO_0005813Cellular componentcentrosome
GO_0005829Cellular componentcytosol
GO_0034451Cellular componentcentriolar satellite
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCEP72
Protein nameCentrosomal protein of 72 kDa
Centrosomal protein of 72 kDa (Cep72)
SynonymsKIAA1519
DescriptionFUNCTION: Involved in the recruitment of key centrosomal proteins to the centrosome. Provides centrosomal microtubule-nucleation activity on the gamma-tubulin ring complexes (gamma-TuRCs) and has critical roles in forming a focused bipolar spindle, which is needed for proper tension generation between sister chromatids. Required for localization of KIZ, AKAP9 and gamma-tubulin ring complexes (gamma-TuRCs) . Involved in centriole duplication. Required for CDK5RAP22, CEP152, WDR62 and CEP63 centrosomal localization and promotes the centrosomal localization of CDK2 . .

AccessionsA0A0G2JR44
ENST00000625371.1
ENST00000264935.6 [Q9P209-1]
Q9P209