CENPQ report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CENPQ at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CENPQ at tissue level.

III. Associated gene sets

GO_1905342Biological processpositive regulation of protein localization to kinetochore
GO_0007059Biological processchromosome segregation
GO_0051310Biological processmetaphase chromosome alignment
GO_0015629Cellular componentactin cytoskeleton
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0000939Cellular componentinner kinetochore
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCENPQ
Protein nameCentromere protein Q (CENP-Q)
SynonymsC6orf139
DescriptionFUNCTION: Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex . Plays an important role in chromosome congression and in the recruitment of CENP-O complex (which comprises CENPO, CENPP, CENPQ and CENPU), CENPE and PLK1 to the kinetochores . .

AccessionsQ7L2Z9
ENST00000335783.4