I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 25% ± 5% | |
| endothelial cell | 4 studies | 21% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 25% ± 5% | |
| endothelial cell | 4 studies | 21% ± 4% |
Insufficient scRNA-seq data for expression of CENPB at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| adrenal gland | 100% | 5005.86 | 258 / 258 | 100% | 120.33 | 230 / 230 |
| esophagus | 100% | 6783.83 | 1445 / 1445 | 100% | 117.34 | 183 / 183 |
| ovary | 100% | 4692.86 | 180 / 180 | 100% | 109.88 | 430 / 430 |
| skin | 100% | 7140.14 | 1809 / 1809 | 100% | 168.12 | 472 / 472 |
| thymus | 100% | 5066.54 | 653 / 653 | 100% | 142.22 | 605 / 605 |
| brain | 100% | 8256.72 | 2640 / 2642 | 100% | 205.42 | 705 / 705 |
| uterus | 100% | 5768.38 | 170 / 170 | 100% | 163.65 | 458 / 459 |
| kidney | 100% | 4016.09 | 89 / 89 | 100% | 111.33 | 899 / 901 |
| liver | 100% | 2963.21 | 226 / 226 | 100% | 89.26 | 405 / 406 |
| intestine | 100% | 6180.96 | 966 / 966 | 100% | 141.85 | 525 / 527 |
| prostate | 100% | 5637.58 | 245 / 245 | 99% | 102.74 | 499 / 502 |
| breast | 100% | 5592.28 | 459 / 459 | 99% | 144.67 | 1111 / 1118 |
| stomach | 100% | 4850.54 | 359 / 359 | 99% | 134.69 | 284 / 286 |
| lung | 100% | 5033.97 | 577 / 578 | 99% | 126.17 | 1142 / 1155 |
| bladder | 100% | 6497.76 | 21 / 21 | 99% | 139.78 | 497 / 504 |
| pancreas | 98% | 3010.27 | 323 / 328 | 100% | 133.03 | 178 / 178 |
| adipose | 100% | 5676.98 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 149.02 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 92.44 | 29 / 29 |
| muscle | 100% | 7293.07 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 4768.51 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 142.34 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 97.34 | 1 / 1 |
| blood vessel | 100% | 5790.39 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| heart | 100% | 4068.47 | 857 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 80% | 2004.81 | 746 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0000775 | Cellular component | chromosome, centromeric region |
| GO_0000779 | Cellular component | condensed chromosome, centromeric region |
| GO_0005694 | Cellular component | chromosome |
| GO_0016604 | Cellular component | nuclear body |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005721 | Cellular component | pericentric heterochromatin |
| GO_0005634 | Cellular component | nucleus |
| GO_0003677 | Molecular function | DNA binding |
| GO_0003696 | Molecular function | satellite DNA binding |
| GO_0043565 | Molecular function | sequence-specific DNA binding |
| GO_0003682 | Molecular function | chromatin binding |
| GO_0019237 | Molecular function | centromeric DNA binding |
| Gene name | CENPB |
| Protein name | Major centromere autoantigen B (Centromere protein B) (CENP-B) |
| Synonyms | |
| Description | FUNCTION: Interacts with centromeric heterochromatin in chromosomes and binds to a specific 17 bp subset of alphoid satellite DNA, called the CENP-B box . May organize arrays of centromere satellite DNA into a higher-order structure which then directs centromere formation and kinetochore assembly in mammalian chromosomes (Probable). . |
| Accessions | P07199 ENST00000379751.5 |
