CELA2A report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CELA2A at tissue level.

III. Associated gene sets

GO_1901143Biological processinsulin catabolic process
GO_0050796Biological processregulation of insulin secretion
GO_0032868Biological processresponse to insulin
GO_0006508Biological processproteolysis
GO_0090330Biological processregulation of platelet aggregation
GO_0005615Cellular componentextracellular space
GO_0036457Cellular componentkeratohyalin granule
GO_0005829Cellular componentcytosol
GO_0005576Cellular componentextracellular region
GO_0017171Molecular functionserine hydrolase activity
GO_0004175Molecular functionendopeptidase activity
GO_0005515Molecular functionprotein binding
GO_0004252Molecular functionserine-type endopeptidase activity

IV. Literature review

[source]
Gene nameCELA2A
Protein nameChymotrypsin-like elastase family member 2A (EC 3.4.21.71) (Elastase-2A)
SynonymsELA2A
DescriptionFUNCTION: Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and increases insulin sensitivity. .

AccessionsP08217
ENST00000359621.5