Name | Number of supported studies | Average coverage | |
---|---|---|---|
acinar cell | 3 studies | 70% ± 6% |
Insufficient scRNA-seq data for expression of CELA2A at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
pancreas | 100% | 253497.12 | 328 / 328 | 53% | 539.39 | 95 / 178 |
adrenal gland | 93% | 110.42 | 240 / 258 | 3% | 0.16 | 8 / 230 |
stomach | 77% | 48.08 | 277 / 359 | 4% | 1.03 | 11 / 286 |
spleen | 78% | 41.25 | 189 / 241 | 0% | 0 | 0 / 0 |
ovary | 71% | 44.66 | 128 / 180 | 1% | 0.03 | 4 / 430 |
uterus | 68% | 28.72 | 116 / 170 | 0% | 0.01 | 2 / 459 |
liver | 65% | 51.08 | 148 / 226 | 0% | 0.02 | 2 / 406 |
bladder | 62% | 17.29 | 13 / 21 | 0% | 0.01 | 2 / 504 |
brain | 51% | 22.09 | 1354 / 2642 | 6% | 0.09 | 44 / 705 |
prostate | 56% | 48.36 | 136 / 245 | 0% | 0.00 | 1 / 502 |
esophagus | 53% | 38.64 | 763 / 1445 | 2% | 0.04 | 3 / 183 |
intestine | 51% | 32.54 | 495 / 966 | 3% | 10.04 | 16 / 527 |
kidney | 53% | 25.22 | 47 / 89 | 0% | 0.01 | 3 / 901 |
lung | 46% | 24.57 | 267 / 578 | 0% | 0.01 | 5 / 1155 |
breast | 44% | 83.10 | 204 / 459 | 0% | 0.04 | 3 / 1118 |
blood vessel | 44% | 82.91 | 593 / 1335 | 0% | 0 | 0 / 0 |
thymus | 44% | 22.14 | 287 / 653 | 0% | 0.03 | 1 / 605 |
adipose | 44% | 113.34 | 528 / 1204 | 0% | 0 | 0 / 0 |
skin | 39% | 27.60 | 707 / 1809 | 0% | 0.01 | 2 / 472 |
peripheral blood | 38% | 21.20 | 356 / 929 | 0% | 0 | 0 / 0 |
heart | 37% | 25.54 | 320 / 861 | 0% | 0 | 0 / 0 |
muscle | 31% | 17.11 | 251 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 2% | 0.04 | 1 / 45 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_1901143 | Biological process | insulin catabolic process |
GO_0050796 | Biological process | regulation of insulin secretion |
GO_0032868 | Biological process | response to insulin |
GO_0006508 | Biological process | proteolysis |
GO_0090330 | Biological process | regulation of platelet aggregation |
GO_0005615 | Cellular component | extracellular space |
GO_0036457 | Cellular component | keratohyalin granule |
GO_0005829 | Cellular component | cytosol |
GO_0005576 | Cellular component | extracellular region |
GO_0017171 | Molecular function | serine hydrolase activity |
GO_0004175 | Molecular function | endopeptidase activity |
GO_0005515 | Molecular function | protein binding |
GO_0004252 | Molecular function | serine-type endopeptidase activity |
Gene name | CELA2A |
Protein name | Chymotrypsin-like elastase family member 2A (EC 3.4.21.71) (Elastase-2A) |
Synonyms | ELA2A |
Description | FUNCTION: Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and increases insulin sensitivity. . |
Accessions | P08217 ENST00000359621.5 |