CEL | OmnibusX

Name	Number of supported studies	Average coverage
ionocyte	4 studies	37% ± 1%	Explore
acinar cell	3 studies	80% ± 15%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of CEL at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
pancreas	100%	1240029.77	328 / 328	65%	1323.31	116 / 178
uterus	96%	243.32	164 / 170	60%	35.60	274 / 459
bladder	100%	237.62	21 / 21	54%	24.62	273 / 504
ovary	99%	487.32	179 / 180	49%	19.09	212 / 430
intestine	89%	225.41	856 / 966	55%	73.36	288 / 527
stomach	89%	251.01	320 / 359	50%	175.80	144 / 286
esophagus	84%	294.69	1219 / 1445	48%	44.99	88 / 183
lung	78%	147.05	452 / 578	39%	22.93	454 / 1155
adrenal gland	95%	207.98	246 / 258	16%	5.33	37 / 230
prostate	98%	372.34	240 / 245	12%	2.52	58 / 502
kidney	100%	430.26	89 / 89	8%	4.62	75 / 901
thymus	95%	199.68	618 / 653	12%	2.65	73 / 605
liver	91%	218.24	206 / 226	10%	1.29	39 / 406
spleen	97%	239.98	233 / 241	0%	0	0 / 0
breast	81%	725.87	370 / 459	16%	6.28	174 / 1118
brain	85%	224.01	2256 / 2642	8%	0.34	55 / 705
heart	91%	255.80	785 / 861	0%	0	0 / 0
skin	84%	312.68	1518 / 1809	1%	0.06	7 / 472
blood vessel	78%	373.64	1038 / 1335	0%	0	0 / 0
adipose	76%	563.15	919 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	71%	31.51	32 / 45
peripheral blood	46%	86.79	428 / 929	0%	0	0 / 0
muscle	45%	76.12	359 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	3%	0.09	2 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0030157	Biological process	pancreatic juice secretion
GO_0006629	Biological process	lipid metabolic process
GO_0030299	Biological process	intestinal cholesterol absorption
GO_0042572	Biological process	retinol metabolic process
GO_0046514	Biological process	ceramide catabolic process
GO_0005615	Cellular component	extracellular space
GO_0070062	Cellular component	extracellular exosome
GO_0005576	Cellular component	extracellular region
GO_0005737	Cellular component	cytoplasm
GO_0004806	Molecular function	triglyceride lipase activity
GO_0004771	Molecular function	sterol esterase activity
GO_0008201	Molecular function	heparin binding
GO_0016787	Molecular function	hydrolase activity
GO_0050253	Molecular function	retinyl-palmitate esterase activity
GO_0003824	Molecular function	catalytic activity
GO_0008126	Molecular function	acetylesterase activity
GO_0005515	Molecular function	protein binding

Gene name	CEL
Protein name	Carboxyl ester lipase (Bile salt-stimulated lipase), isoform CRA_a (Carboxyl ester lipase-like protein) Bile salt-activated lipase (BAL) (EC 3.1.1.13) (EC 3.1.1.3) (EC 3.1.1.6) (Bile salt-stimulated lipase) (BSSL) (Bucelipase) (Carboxyl ester lipase) (Cholesterol esterase) (Pancreatic lysophospholipase) (Sterol esterase)
Synonyms	hCG_2032990 CELL BAL
Description	FUNCTION: Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs) . Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs (By similarity). Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins . .
Accessions	ENST00000372080.8 [P19835-1] P19835 Q14018

CEL report