CDKN2C report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CDKN2C at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CDKN2C at tissue level.

III. Associated gene sets

GO_0000079Biological processregulation of cyclin-dependent protein serine/threonine kinase activity
GO_0008285Biological processnegative regulation of cell population proliferation
GO_2000045Biological processregulation of G1/S transition of mitotic cell cycle
GO_2000647Biological processnegative regulation of stem cell proliferation
GO_0072089Biological processstem cell proliferation
GO_0048709Biological processoligodendrocyte differentiation
GO_0042326Biological processnegative regulation of phosphorylation
GO_0030308Biological processnegative regulation of cell growth
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0004861Molecular functioncyclin-dependent protein serine/threonine kinase inhibitor activity
GO_0019901Molecular functionprotein kinase binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCDKN2C
Protein nameCyclin-dependent kinase inhibitor 2C
CDKN2C protein (Cyclin-dependent kinase inhibitor 2C (P18, inhibits CDK4), isoform CRA_a) (cDNA FLJ33851 fis, clone CTONG2005635, highly similar to CYCLIN-DEPENDENT KINASE 6 INHIBITOR)
Cyclin-dependent kinase 4 inhibitor C (Cyclin-dependent kinase 6 inhibitor) (p18-INK4c) (p18-INK6)
SynonymsCDKN6
hCG_40289
DescriptionFUNCTION: Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB.

AccessionsQ9P1T2
Q6ICV4
P42773
ENST00000371761.4
ENST00000262662.5
ENST00000396148.2