Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 3 studies | 21% ± 4% |
Insufficient scRNA-seq data for expression of CDK20 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 913.69 | 245 / 245 | 99% | 7.78 | 496 / 502 |
brain | 99% | 1101.57 | 2612 / 2642 | 100% | 13.57 | 703 / 705 |
adrenal gland | 100% | 1957.79 | 258 / 258 | 98% | 10.00 | 226 / 230 |
ovary | 100% | 1290.73 | 180 / 180 | 98% | 7.78 | 422 / 430 |
thymus | 100% | 1168.75 | 653 / 653 | 98% | 8.14 | 590 / 605 |
pancreas | 100% | 539.78 | 327 / 328 | 97% | 5.99 | 172 / 178 |
kidney | 100% | 914.11 | 89 / 89 | 96% | 8.61 | 864 / 901 |
breast | 98% | 548.44 | 448 / 459 | 97% | 7.25 | 1083 / 1118 |
skin | 100% | 440.08 | 1800 / 1809 | 94% | 6.05 | 445 / 472 |
uterus | 100% | 1105.91 | 170 / 170 | 85% | 5.35 | 389 / 459 |
bladder | 100% | 1073.00 | 21 / 21 | 84% | 4.18 | 421 / 504 |
lung | 96% | 490.29 | 554 / 578 | 81% | 3.93 | 940 / 1155 |
intestine | 100% | 838.14 | 965 / 966 | 76% | 3.14 | 403 / 527 |
stomach | 98% | 541.78 | 353 / 359 | 69% | 2.76 | 198 / 286 |
esophagus | 98% | 533.53 | 1422 / 1445 | 55% | 2.23 | 100 / 183 |
liver | 86% | 246.16 | 194 / 226 | 43% | 1.79 | 176 / 406 |
eye | 0% | 0 | 0 / 0 | 100% | 8.76 | 80 / 80 |
ureter | 0% | 0 | 0 / 0 | 100% | 4.08 | 1 / 1 |
blood vessel | 97% | 352.19 | 1291 / 1335 | 0% | 0 | 0 / 0 |
adipose | 94% | 372.80 | 1133 / 1204 | 0% | 0 | 0 / 0 |
spleen | 93% | 261.19 | 224 / 241 | 0% | 0 | 0 / 0 |
heart | 72% | 219.71 | 621 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 69% | 3.17 | 31 / 45 |
muscle | 9% | 18.38 | 73 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 7% | 0.25 | 2 / 29 |
peripheral blood | 2% | 4.84 | 21 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0061512 | Biological process | protein localization to cilium |
GO_0021508 | Biological process | floor plate formation |
GO_1903317 | Biological process | regulation of protein maturation |
GO_0045879 | Biological process | negative regulation of smoothened signaling pathway |
GO_0051301 | Biological process | cell division |
GO_0060021 | Biological process | roof of mouth development |
GO_0048706 | Biological process | embryonic skeletal system development |
GO_0031076 | Biological process | embryonic camera-type eye development |
GO_0001843 | Biological process | neural tube closure |
GO_0006468 | Biological process | protein phosphorylation |
GO_0051726 | Biological process | regulation of cell cycle |
GO_1990403 | Biological process | embryonic brain development |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005929 | Cellular component | cilium |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0106310 | Molecular function | protein serine kinase activity |
GO_0004674 | Molecular function | protein serine/threonine kinase activity |
GO_0005524 | Molecular function | ATP binding |
GO_0005515 | Molecular function | protein binding |
GO_0004693 | Molecular function | cyclin-dependent protein serine/threonine kinase activity |
Gene name | CDK20 |
Protein name | Cyclin-dependent kinase 20 (EC 2.7.11.22) (Cell cycle-related kinase) (Cell division protein kinase 20) Cyclin-dependent kinase 20 (EC 2.7.11.22) (CDK-activating kinase p42) (CAK-kinase p42) (Cell cycle-related kinase) (Cell division protein kinase 20) (Cyclin-dependent protein kinase H) (Cyclin-kinase-activating kinase p42) |
Synonyms | CCRK hCG_1743717 CDCH |
Description | FUNCTION: Required for high-level Shh responses in the developing neural tube. Together with TBC1D32, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling (By similarity). Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160'. . |
Accessions | A0A0S2Z566 A0A0S2Z5B6 Q8IZL9 ENST00000375871.8 [Q8IZL9-2] A0A0S2Z557 A0A0S2Z562 ENST00000336654.9 [Q8IZL9-4] ENST00000375883.7 [Q8IZL9-5] A0A0S2Z552 ENST00000605159.5 [Q8IZL9-3] ENST00000325303.9 [Q8IZL9-1] A0A0S2Z535 |