CDK16 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007283Biological processspermatogenesis
GO_0030252Biological processgrowth hormone secretion
GO_0031175Biological processneuron projection development
GO_0006887Biological processexocytosis
GO_0061178Biological processregulation of insulin secretion involved in cellular response to glucose stimulus
GO_0010508Biological processpositive regulation of autophagy
GO_0006468Biological processprotein phosphorylation
GO_0051726Biological processregulation of cell cycle
GO_0005886Cellular componentplasma membrane
GO_0009898Cellular componentcytoplasmic side of plasma membrane
GO_0043005Cellular componentneuron projection
GO_0000307Cellular componentcyclin-dependent protein kinase holoenzyme complex
GO_0005829Cellular componentcytosol
GO_0008021Cellular componentsynaptic vesicle
GO_0015630Cellular componentmicrotubule cytoskeleton
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0106310Molecular functionprotein serine kinase activity
GO_0004674Molecular functionprotein serine/threonine kinase activity
GO_0005524Molecular functionATP binding
GO_0005515Molecular functionprotein binding
GO_0004693Molecular functioncyclin-dependent protein serine/threonine kinase activity

IV. Literature review

[source]
Gene nameCDK16
Protein nameCyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1)
Cyclin dependent kinase 16
SynonymsPCTAIRE1
PCTK1
DescriptionFUNCTION: Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis. Regulates GH1 release by brain neurons. Phosphorylates NSF, and thereby regulates NSF oligomerization. Required for normal spermatogenesis. Regulates neuron differentiation and dendrite development (By similarity). Plays a role in the regulation of insulin secretion in response to changes in blood glucose levels. Can phosphorylate CCNY at 'Ser-336' (in vitro). .

AccessionsH0YC60
ENST00000523034.1
E5RIY8
ENST00000357227.9 [Q00536-1]
ENST00000276052.10 [Q00536-2]
E5RJM2
ENST00000519758.5
H0YBX5
H0YAZ9
ENST00000517426.5
E5RGN0
Q00536
ENST00000518391.5
ENST00000520893.5
E5RIU4
ENST00000457458.6 [Q00536-3]
ENST00000462827.2
H0YC36
ENST00000520141.5
E5RJQ8
ENST00000523344.5
ENST00000522883.1
ENST00000518022.5 [Q00536-1]