CDCA8 | OmnibusX

Name	Number of supported studies	Average coverage
CD4-positive, alpha-beta T cell	4 studies	24% ± 8%	Explore
natural killer cell	3 studies	18% ± 1%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of CDCA8 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
skin	99%	1087.75	1789 / 1809	95%	38.25	448 / 472
stomach	77%	284.03	278 / 359	98%	52.72	280 / 286
lung	79%	175.63	455 / 578	92%	39.24	1059 / 1155
breast	71%	93.50	324 / 459	93%	36.20	1036 / 1118
intestine	63%	419.48	606 / 966	98%	61.04	518 / 527
esophagus	55%	364.85	789 / 1445	99%	49.20	181 / 183
uterus	48%	56.99	82 / 170	98%	64.28	449 / 459
bladder	38%	48.33	8 / 21	96%	53.39	482 / 504
ovary	27%	39.58	48 / 180	98%	46.80	423 / 430
pancreas	22%	23.45	72 / 328	80%	19.50	143 / 178
lymph node	0%	0	0 / 0	100%	68.08	29 / 29
tonsil	0%	0	0 / 0	100%	68.14	45 / 45
ureter	0%	0	0 / 0	100%	16.15	1 / 1
spleen	100%	546.56	240 / 241	0%	0	0 / 0
adrenal gland	68%	107.51	175 / 258	18%	4.61	42 / 230
brain	44%	43.59	1157 / 2642	40%	12.15	281 / 705
prostate	60%	74.25	148 / 245	23%	3.06	114 / 502
peripheral blood	82%	1381.66	766 / 929	0%	0	0 / 0
liver	27%	61.34	60 / 226	49%	10.51	197 / 406
thymus	54%	63.68	350 / 653	18%	11.01	106 / 605
adipose	59%	79.67	707 / 1204	0%	0	0 / 0
kidney	39%	78.02	35 / 89	14%	2.53	123 / 901
blood vessel	26%	29.50	348 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	11%	1.35	9 / 80
heart	10%	14.91	88 / 861	0%	0	0 / 0
muscle	3%	3.45	28 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0000278	Biological process	mitotic cell cycle
GO_0000070	Biological process	mitotic sister chromatid segregation
GO_1901970	Biological process	positive regulation of mitotic sister chromatid separation
GO_0000281	Biological process	mitotic cytokinesis
GO_0090307	Biological process	mitotic spindle assembly
GO_0051256	Biological process	mitotic spindle midzone assembly
GO_0051276	Biological process	chromosome organization
GO_0090267	Biological process	positive regulation of mitotic cell cycle spindle assembly checkpoint
GO_1902425	Biological process	positive regulation of attachment of mitotic spindle microtubules to kinetochore
GO_1903490	Biological process	positive regulation of mitotic cytokinesis
GO_0007080	Biological process	mitotic metaphase chromosome alignment
GO_0000775	Cellular component	chromosome, centromeric region
GO_0005730	Cellular component	nucleolus
GO_0030496	Cellular component	midbody
GO_0010369	Cellular component	chromocenter
GO_0032991	Cellular component	protein-containing complex
GO_0005654	Cellular component	nucleoplasm
GO_0032133	Cellular component	chromosome passenger complex
GO_0045171	Cellular component	intercellular bridge
GO_0051233	Cellular component	spindle midzone
GO_0005829	Cellular component	cytosol
GO_0015630	Cellular component	microtubule cytoskeleton
GO_0005515	Molecular function	protein binding

Gene name	CDCA8
Protein name	Borealin (Cell division cycle-associated protein 8) (Dasra-B) (hDasra-B) (Pluripotent embryonic stem cell-related gene 3 protein)
Synonyms	PESCRG3
Description	FUNCTION: Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment. .
Accessions	Q53HL2 ENST00000373055.6 ENST00000327331.2

CDCA8 report