CDC45 | OmnibusX

Name	Number of supported studies	Average coverage
transit amplifying cell	3 studies	24% ± 8%	Explore
natural killer cell	3 studies	20% ± 4%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of CDC45 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
skin	90%	531.06	1633 / 1809	96%	24.22	455 / 472
lung	80%	118.89	463 / 578	87%	23.51	1001 / 1155
intestine	56%	149.60	544 / 966	96%	23.13	507 / 527
stomach	53%	108.77	189 / 359	96%	19.88	274 / 286
esophagus	48%	194.29	688 / 1445	98%	20.99	180 / 183
bladder	33%	27.76	7 / 21	95%	24.94	481 / 504
breast	46%	34.96	210 / 459	82%	13.19	920 / 1118
uterus	22%	19.05	37 / 170	98%	36.00	451 / 459
ovary	14%	17.93	26 / 180	90%	12.11	387 / 430
lymph node	0%	0	0 / 0	100%	43.84	29 / 29
tonsil	0%	0	0 / 0	100%	44.73	45 / 45
ureter	0%	0	0 / 0	100%	13.11	1 / 1
spleen	98%	300.07	236 / 241	0%	0	0 / 0
liver	31%	59.90	71 / 226	55%	6.21	222 / 406
pancreas	13%	8.22	41 / 328	69%	7.63	123 / 178
adrenal gland	56%	51.24	144 / 258	21%	2.41	49 / 230
peripheral blood	73%	604.52	676 / 929	0%	0	0 / 0
prostate	51%	41.41	125 / 245	21%	1.59	107 / 502
thymus	30%	19.55	195 / 653	25%	6.55	154 / 605
brain	4%	2.36	104 / 2642	44%	7.12	311 / 705
adipose	45%	35.58	544 / 1204	0%	0	0 / 0
kidney	28%	37.29	25 / 89	17%	1.32	153 / 901
eye	0%	0	0 / 0	26%	1.48	21 / 80
blood vessel	24%	15.94	315 / 1335	0%	0	0 / 0
heart	17%	12.89	147 / 861	0%	0	0 / 0
muscle	8%	4.14	64 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0000727	Biological process	double-strand break repair via break-induced replication
GO_1902977	Biological process	mitotic DNA replication preinitiation complex assembly
GO_0006268	Biological process	DNA unwinding involved in DNA replication
GO_0006270	Biological process	DNA replication initiation
GO_0000076	Biological process	DNA replication checkpoint signaling
GO_0005813	Cellular component	centrosome
GO_0071162	Cellular component	CMG complex
GO_0036064	Cellular component	ciliary basal body
GO_0005654	Cellular component	nucleoplasm
GO_0031261	Cellular component	DNA replication preinitiation complex
GO_0005634	Cellular component	nucleus
GO_0005515	Molecular function	protein binding
GO_0003697	Molecular function	single-stranded DNA binding
GO_0003682	Molecular function	chromatin binding
GO_0003688	Molecular function	DNA replication origin binding

Gene name	CDC45
Protein name	Cell division control protein 45 homolog (PORC-PI-1) Cell division cycle 45
Synonyms	CDC45L2 UNQ374/PRO710 CDC45L
Description	FUNCTION: Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. .
Accessions	ENST00000438587.6 ENST00000455750.6 A0A5F9ZH29 ENST00000407835.6 ENST00000404724.7 [O75419-2] C9J911 O75419 ENST00000437685.6 [O75419-3] C9K087 H7BZ91 ENST00000672837.1 A0A5F9ZI22 ENST00000671972.1 ENST00000428937.1 ENST00000263201.7 [O75419-1] A0A5K1VW85

CDC45 report