Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell of lymphatic vessel | 11 studies | 33% ± 13% | |
goblet cell | 9 studies | 56% ± 12% | |
endothelial cell | 9 studies | 24% ± 7% | |
epithelial cell | 9 studies | 41% ± 16% | |
fibroblast | 7 studies | 22% ± 6% | |
pericyte | 5 studies | 20% ± 4% | |
respiratory goblet cell | 4 studies | 19% ± 2% | |
basal cell | 4 studies | 34% ± 17% | |
enterocyte | 4 studies | 24% ± 8% | |
secretory cell | 4 studies | 46% ± 11% | |
transit amplifying cell | 3 studies | 34% ± 15% | |
endothelial cell of artery | 3 studies | 23% ± 7% | |
luminal cell of prostate epithelium | 3 studies | 48% ± 7% | |
endothelial cell of vascular tree | 3 studies | 20% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
intestine | 100% | 2004.60 | 966 / 966 | 98% | 206.94 | 519 / 527 |
stomach | 98% | 569.87 | 351 / 359 | 97% | 213.99 | 277 / 286 |
prostate | 100% | 2296.50 | 245 / 245 | 89% | 118.98 | 449 / 502 |
bladder | 100% | 1544.14 | 21 / 21 | 80% | 109.34 | 405 / 504 |
esophagus | 99% | 520.42 | 1430 / 1445 | 79% | 119.84 | 144 / 183 |
pancreas | 82% | 286.12 | 270 / 328 | 94% | 108.93 | 167 / 178 |
ovary | 95% | 463.68 | 171 / 180 | 81% | 63.17 | 347 / 430 |
thymus | 98% | 445.60 | 641 / 653 | 73% | 32.10 | 442 / 605 |
uterus | 100% | 648.79 | 170 / 170 | 65% | 46.43 | 300 / 459 |
skin | 98% | 584.55 | 1770 / 1809 | 54% | 23.85 | 254 / 472 |
lung | 100% | 888.06 | 577 / 578 | 52% | 40.18 | 598 / 1155 |
kidney | 97% | 470.21 | 86 / 89 | 39% | 11.74 | 354 / 901 |
breast | 100% | 889.53 | 459 / 459 | 32% | 10.81 | 353 / 1118 |
adrenal gland | 93% | 281.47 | 241 / 258 | 26% | 9.04 | 60 / 230 |
ureter | 0% | 0 | 0 / 0 | 100% | 91.27 | 1 / 1 |
adipose | 100% | 808.47 | 1200 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 42.58 | 79 / 80 |
blood vessel | 98% | 742.32 | 1306 / 1335 | 0% | 0 | 0 / 0 |
spleen | 94% | 341.80 | 227 / 241 | 0% | 0 | 0 / 0 |
heart | 93% | 413.85 | 803 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 56% | 16.76 | 25 / 45 |
lymph node | 0% | 0 | 0 / 0 | 45% | 9.83 | 13 / 29 |
liver | 14% | 26.79 | 31 / 226 | 7% | 1.85 | 27 / 406 |
muscle | 18% | 34.58 | 141 / 803 | 0% | 0 | 0 / 0 |
brain | 6% | 11.96 | 161 / 2642 | 3% | 1.12 | 21 / 705 |
peripheral blood | 4% | 11.80 | 34 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007266 | Biological process | Rho protein signal transduction |
GO_0007254 | Biological process | JNK cascade |
GO_0008360 | Biological process | regulation of cell shape |
GO_0030838 | Biological process | positive regulation of actin filament polymerization |
GO_0031274 | Biological process | positive regulation of pseudopodium assembly |
GO_0012505 | Cellular component | endomembrane system |
GO_0005856 | Cellular component | cytoskeleton |
GO_0005829 | Cellular component | cytosol |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0031267 | Molecular function | small GTPase binding |
Gene name | CDC42EP5 |
Protein name | Cdc42 effector protein 5 (Binder of Rho GTPases 3) Cdc42 effector protein 5 |
Synonyms | CEP5 BORG3 |
Description | FUNCTION: Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts. Inhibits MAPK8 independently of CDC42 binding. Controls septin organization and this effect is negatively regulated by CDC42 (By similarity). . |
Accessions | ENST00000301200.3 ENST00000617756.1 ENST00000611094.1 ENST00000610368.1 Q6NZY7 A0A0G2JPE9 ENST00000619217.1 ENST00000622855.1 |