CDC42BPG report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CDC42BPG at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CDC42BPG at tissue level.

III. Associated gene sets

GO_0018107Biological processpeptidyl-threonine phosphorylation
GO_0030036Biological processactin cytoskeleton organization
GO_0006468Biological processprotein phosphorylation
GO_0031032Biological processactomyosin structure organization
GO_0005856Cellular componentcytoskeleton
GO_0005829Cellular componentcytosol
GO_0034451Cellular componentcentriolar satellite
GO_0005737Cellular componentcytoplasm
GO_0031252Cellular componentcell leading edge
GO_0005524Molecular functionATP binding
GO_0004674Molecular functionprotein serine/threonine kinase activity
GO_0106310Molecular functionprotein serine kinase activity
GO_0005515Molecular functionprotein binding
GO_0000287Molecular functionmagnesium ion binding

IV. Literature review

[source]
Gene nameCDC42BPG
Protein nameSerine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42-binding protein kinase gamma) (DMPK-like gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (MRCK gamma) (MRCKG) (Myotonic dystrophy protein kinase-like gamma) (Myotonic dystrophy protein kinase-like alpha)
SynonymsDMPK2
DescriptionFUNCTION: May act as a downstream effector of CDC42 in cytoskeletal reorganization. Contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and thus MLC2 phosphorylation (By similarity). .

AccessionsQ6DT37
ENST00000342711.6