CD93 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0042116Biological processmacrophage activation
GO_0098609Biological processcell-cell adhesion
GO_0006909Biological processphagocytosis
GO_0009986Cellular componentcell surface
GO_0030667Cellular componentsecretory granule membrane
GO_0070821Cellular componenttertiary granule membrane
GO_0035579Cellular componentspecific granule membrane
GO_0005886Cellular componentplasma membrane
GO_0101003Cellular componentficolin-1-rich granule membrane
GO_0038023Molecular functionsignaling receptor activity
GO_0005509Molecular functioncalcium ion binding
GO_0030246Molecular functioncarbohydrate binding
GO_0005515Molecular functionprotein binding
GO_0001849Molecular functioncomplement component C1q complex binding

IV. Literature review

[source]
Gene nameCD93
Protein nameC1q receptor protein
Complement component C1q receptor (C1q/MBL/SPA receptor) (C1qR) (C1qR(p)) (C1qRp) (CDw93) (Complement component 1 q subcomponent receptor 1) (Matrix-remodeling-associated protein 4) (CD antigen CD93)
SynonymsMXRA4
C1QR1
DescriptionFUNCTION: Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion.

AccessionsQ9NPY3
ENST00000246006.5
Q8IXK1