Insufficient scRNA-seq data for expression of CCN6 at single-cell level.
Insufficient scRNA-seq data for expression of CCN6 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 85% | 24.69 | 153 / 180 | 83% | 8.33 | 356 / 430 |
bladder | 90% | 33.24 | 19 / 21 | 46% | 6.60 | 230 / 504 |
uterus | 99% | 61.24 | 168 / 170 | 27% | 3.20 | 126 / 459 |
esophagus | 75% | 20.70 | 1081 / 1445 | 51% | 4.51 | 93 / 183 |
breast | 92% | 54.11 | 424 / 459 | 32% | 2.28 | 363 / 1118 |
kidney | 98% | 81.78 | 87 / 89 | 23% | 3.43 | 211 / 901 |
intestine | 80% | 22.74 | 776 / 966 | 35% | 4.85 | 183 / 527 |
stomach | 74% | 28.96 | 266 / 359 | 38% | 3.47 | 110 / 286 |
prostate | 94% | 38.19 | 230 / 245 | 8% | 0.11 | 38 / 502 |
skin | 85% | 110.16 | 1533 / 1809 | 15% | 2.25 | 72 / 472 |
lung | 61% | 13.68 | 352 / 578 | 32% | 2.60 | 374 / 1155 |
brain | 90% | 88.06 | 2386 / 2642 | 1% | 0.04 | 9 / 705 |
thymus | 76% | 18.82 | 499 / 653 | 12% | 0.30 | 73 / 605 |
adipose | 84% | 23.59 | 1007 / 1204 | 0% | 0 | 0 / 0 |
liver | 73% | 23.16 | 166 / 226 | 2% | 0.10 | 9 / 406 |
pancreas | 28% | 4.54 | 92 / 328 | 47% | 6.55 | 83 / 178 |
spleen | 74% | 16.09 | 178 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 67% | 15.21 | 901 / 1335 | 0% | 0 | 0 / 0 |
heart | 51% | 10.35 | 442 / 861 | 0% | 0 | 0 / 0 |
adrenal gland | 38% | 7.37 | 97 / 258 | 0% | 0 | 0 / 230 |
muscle | 18% | 3.30 | 148 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 16% | 1.28 | 7 / 45 |
peripheral blood | 6% | 0.95 | 55 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.24 | 1 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_1903426 | Biological process | regulation of reactive oxygen species biosynthetic process |
GO_0007165 | Biological process | signal transduction |
GO_0051881 | Biological process | regulation of mitochondrial membrane potential |
GO_0008285 | Biological process | negative regulation of cell population proliferation |
GO_0045597 | Biological process | positive regulation of cell differentiation |
GO_0007155 | Biological process | cell adhesion |
GO_0007267 | Biological process | cell-cell signaling |
GO_0016525 | Biological process | negative regulation of angiogenesis |
GO_0005615 | Cellular component | extracellular space |
GO_0031012 | Cellular component | extracellular matrix |
GO_0005739 | Cellular component | mitochondrion |
GO_0008201 | Molecular function | heparin binding |
GO_0005178 | Molecular function | integrin binding |
GO_0008083 | Molecular function | growth factor activity |
Gene name | CCN6 |
Protein name | Cellular communication network factor 6 (WNT1 inducible signaling pathway protein 3, isoform CRA_b) Cellular communication network factor 6 (CCN family member 6) (WNT1-inducible-signaling pathway protein 3) (WISP-3) Cellular communication network factor 6 Lost in inflammatory breast cancer tumor suppressor protein (WNT1 inducible signaling pathway protein 3, isoform CRA_d) WISP3 protein |
Synonyms | UNQ462/PRO790/PRO956 hCG_34804 WISP3 LIBC |
Description | FUNCTION: Plays a role in mitochondrial electron transport and mitochondrial respiration . Through its regulation of the mitochondrial function may play a role in normal postnatal skeletal growth and cartilage homeostasis . . |
Accessions | ENST00000454589.5 ENST00000604763.5 [O95389-1] G3V0J1 F8WC24 ENST00000368666.7 [O95389-1] ENST00000230529.9 [O95389-1] ENST00000674325.1 I6L968 O95389 A0A6I8PRG4 ENST00000368664.7 Q3T1A9 ENST00000483439.1 O95958 I6L9I2 |