CCDC62 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CCDC62 at tissue level.

III. Associated gene sets

GO_0071392Biological processcellular response to estradiol stimulus
GO_0001835Biological processblastocyst hatching
GO_0007286Biological processspermatid development
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0001669Cellular componentacrosomal vesicle
GO_0005634Cellular componentnucleus
GO_0030374Molecular functionnuclear receptor coactivator activity
GO_0005515Molecular functionprotein binding
GO_0030331Molecular functionnuclear estrogen receptor binding

IV. Literature review

[source]
Gene nameCCDC62
Protein nameCoiled-coil domain-containing protein 62 (Protein TSP-NY) (Protein aaa)
Coiled-coil domain containing 62
SynonymshCG_2015662
DescriptionFUNCTION: Nuclear receptor coactivator that can enhance preferentially estrogen receptors ESR1 and ESR2 transactivation. Modulates also progesterone/PGR, glucocorticoid/NR3C1 and androgen/AR receptors transactivation, although at lower level; little effect on vitamin D receptor/VDR. Required for normal spermiogenesis. It probably plays a role in acrosome formation (By similarity). .

AccessionsQ6P9F0
ENST00000253079.11 [Q6P9F0-1]
ENST00000539171.1
F5H0F1
ENST00000341952.8 [Q6P9F0-2]
ENST00000392440.3
A0A024RBT8
ENST00000392441.8 [Q6P9F0-2]
ENST00000537566.5 [Q6P9F0-3]