CATSPER4 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CATSPER4 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CATSPER4 at tissue level.

III. Associated gene sets

GO_0030317Biological processflagellated sperm motility
GO_0048240Biological processsperm capacitation
GO_0006814Biological processsodium ion transport
GO_0051649Biological processestablishment of localization in cell
GO_0070588Biological processcalcium ion transmembrane transport
GO_0097228Cellular componentsperm principal piece
GO_0036128Cellular componentCatSper complex
GO_0001669Cellular componentacrosomal vesicle
GO_0005886Cellular componentplasma membrane
GO_0005245Molecular functionvoltage-gated calcium channel activity
GO_0005515Molecular functionprotein binding
GO_0005227Molecular functioncalcium-activated cation channel activity

IV. Literature review

[source]
Gene nameCATSPER4
Protein nameCation channel sperm-associated protein 4 (CatSper4)
Cation channel sperm associated 4
Synonyms
DescriptionFUNCTION: Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. .

AccessionsQ7RTX7
ENST00000338855.6
ENST00000456354.7 [Q7RTX7-1]
ENST00000518899.5 [Q7RTX7-2]
J3KNU1